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ChemicalBook >> CAS DataBase List >> Amitriptyline hydrochloride

Amitriptyline hydrochloride

Amitriptyline hydrochloride price.
  • $5 - $2055.9
  • Product name: Amitriptyline hydrochloride
  • CAS: 549-18-8
  • MF: C20H24ClN
  • MW: 313.86
  • EINECS:208-964-6
  • MDL Number:MFCD00012537
  • Synonyms:Amiplin;Normaln;Amitriptyline Hydrochloride (200 mg);Methanol (test Amitriptyline HCl, 1.0 mg/mL as free base);3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride;Amitriptyline hydrochloride 98+%;Amitriptyline hydrochloride solution ;3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Chemtos
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • 1ml of 1mg
  • y0000563
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  • 200mg
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  • 1mL
  • 1g
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  • 10mM(in 1mL DMSO)
  • 50g
  • 100g
  • 250g
  • ManufacturerAK Scientific
  • Product numberJ10484
  • Product descriptionAmitriptyline hydrochloride
  • Packaging100mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65596
  • Product description5-[3-(Dimethylamino)propylidene]dibenzosuberane hydrochloride, 98%
  • Packaging25g
  • Price$130.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65596
  • Product description5-[3-(Dimethylamino)propylidene]dibenzosuberane hydrochloride, 98%
  • Packaging100g
  • Price$350.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging100g
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging25g
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001458
  • Product descriptionAMITRIPTYLINE HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001458
  • Product descriptionAMITRIPTYLINE HYDROCHLORIDE 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2231
  • Product descriptionAmitriptylineHCl
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2231
  • Product descriptionAmitriptylineHCl
  • Packaging1g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2231
  • Product descriptionAmitriptylineHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2231
  • Product descriptionAmitriptylineHCl
  • Packaging5g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS517240
  • Product descriptionAmitriptyline hydrochloride ≥97%
  • Packaging25g
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS517240
  • Product descriptionAmitriptyline hydrochloride ≥97%
  • Packaging5g
  • Price$13
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10484 Amitriptyline hydrochloride 100mg $94 2021-12-16 Buy
Alfa Aesar J65596 5-[3-(Dimethylamino)propylidene]dibenzosuberane hydrochloride, 98% 25g $130.65 2024-03-01 Buy
Alfa Aesar J65596 5-[3-(Dimethylamino)propylidene]dibenzosuberane hydrochloride, 98% 100g $350.65 2024-03-01 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 100g $164 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 100mg $5 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 1g $6 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 5g $10 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 25g $43 2021-12-16 Buy
American Custom Chemicals Corporation API0001458 AMITRIPTYLINE HYDROCHLORIDE 95.00% 1G $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0001458 AMITRIPTYLINE HYDROCHLORIDE 95.00% 10G $2055.9 2021-12-16 Buy
ApexBio Technology B2231 AmitriptylineHCl 1unit $28 2021-12-16 Buy
ApexBio Technology B2231 AmitriptylineHCl 1g $37 2021-12-16 Buy
ApexBio Technology B2231 AmitriptylineHCl 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B2231 AmitriptylineHCl 5g $57 2021-12-16 Buy
Arctom AS517240 Amitriptyline hydrochloride ≥97% 25g $43 2021-12-16 Buy
Arctom AS517240 Amitriptyline hydrochloride ≥97% 5g $13 2021-12-16 Buy

Properties

Melting point :196-197°C
Flash point :11 °C
storage temp. :2-8°C
solubility :H2O: soluble
form :powder
pka :9.4(at 25℃)
color :white to off-white
PH :4.5～6.0 (10g/l, 25℃)
Water Solubility :almost transparency
Merck :14,487
BCS Class :1
CAS DataBase Reference :549-18-8(CAS DataBase Reference)
EPA Substance Registry System :Amitriptyline hydrochloride (549-18-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Amitriptyline is a first generation tricyclic antidepressant. It strongly blocks the serotonin and norepinephrine transporters (Kds = 4.3 and 35 nM, respectively) and inhibits the serotonin 5-HT2A receptor (Ki =20 nM). Amitriptyline also antagonizes histamine H1, muscarinic acetylcholine, and α1-adrenergic receptors (Kis = 1.1, 18, and 27 nM, respectively).

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