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ChemicalBook >> CAS DataBase List >> N'-Nitro-L-arginine-methyl ester hydrochloride

N'-Nitro-L-arginine-methyl ester hydrochloride

N'-Nitro-L-arginine-methyl ester hydrochloride price.
  • $10 - $1504.5
  • Product name: N'-Nitro-L-arginine-methyl ester hydrochloride
  • CAS: 51298-62-5
  • MF: C7H16ClN5O4
  • MW: 269.69
  • EINECS:257-116-1
  • MDL Number:MFCD00039052
  • Synonyms:H-L-Arg(NO2)-OMe*HCl;H-Arg(NOZ)-OMe.HCl;methyl N5-[imino(nitroamino)methyl]-L-ornithine monohydrochloride ;H-Ala(NO2)-OMeHCl;H-Ala(No2)-Omecl;ω-Nitro-L-arginine methyl·hydrochloric acid;NG-Nitro-L-arginine-methyl ester hydrochloride,98%;Nω-Nitro-L-arginine methyl ester hydrochloride ,98%
51 prices
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  • Activate Scientific
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Iris Biotech GmbH
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging5G
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging25g
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS112931
  • Product descriptionH-Arg(NO2)-OMe.HCl 98%
  • Packaging100g
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-52238
  • Product descriptionH-Ala(NO2)-OMehydrochloride 99%
  • Packaging10g
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51453
  • Product descriptionNω-Nitro-L-arginine methyl ester hydrochloride
  • Packaging100g
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH63666
  • Product descriptionNomega-Nitro-L-arginine methyl ester hydrochloride, 98%
  • Packaging5g
  • Price$105
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH63666
  • Product descriptionNomega-Nitro-L-arginine methyl ester hydrochloride, 98%
  • Packaging25g
  • Price$223
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001651
  • Product descriptionH-ARG(NO2)-OME HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$605.17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAAA0001651
  • Product descriptionH-ARG(NO2)-OME HYDROCHLORIDE 95.00%
  • Packaging5G
  • Price$732
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA7088
  • Product descriptionL-NAMEhydrochloride
  • Packaging100mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA7088
  • Product descriptionL-NAMEhydrochloride
  • Packaging10g
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA7088
  • Product descriptionL-NAMEhydrochloride
  • Packaging25g
  • Price$150
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN60352
  • Product descriptionL-NAMEHCl ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134513
  • Product descriptionL-NAME HCl >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134513
  • Product descriptionL-NAME HCl >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134513
  • Product descriptionL-NAME HCl >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 5G $26 2021-12-16 Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 25g $104 2021-12-16 Buy
Activate Scientific AS112931 H-Arg(NO2)-OMe.HCl 98% 100g $333 2021-12-16 Buy
AHH MT-52238 H-Ala(NO2)-OMehydrochloride 99% 10g $330 2021-12-16 Buy
AK Scientific J51453 Nω-Nitro-L-arginine methyl ester hydrochloride 100g $190 2021-12-16 Buy
Alfa Aesar H63666 Nomega-Nitro-L-arginine methyl ester hydrochloride, 98% 5g $105 2024-03-01 Buy
Alfa Aesar H63666 Nomega-Nitro-L-arginine methyl ester hydrochloride, 98% 25g $223 2024-03-01 Buy
American Custom Chemicals Corporation AAA0001651 H-ARG(NO2)-OME HYDROCHLORIDE 95.00% 100MG $605.17 2021-12-16 Buy
American Custom Chemicals Corporation AAA0001651 H-ARG(NO2)-OME HYDROCHLORIDE 95.00% 5G $732 2021-12-16 Buy
ApexBio Technology A7088 L-NAMEhydrochloride 100mg $40 2021-12-16 Buy
ApexBio Technology A7088 L-NAMEhydrochloride 10g $50 2021-12-16 Buy
ApexBio Technology A7088 L-NAMEhydrochloride 25g $150 2021-12-16 Buy
Arctom CFN60352 L-NAMEHCl ≥98% 20mg $30 2021-12-16 Buy
Biorbyt Ltd orb134513 L-NAME HCl >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134513 L-NAME HCl >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb134513 L-NAME HCl >99% 1g $1504.5 2021-12-16 Buy

Properties

Melting point :157-161 °C (dec.)
alpha :14.5 º (c=3, CH3OH)
RTECS :RM2982570
refractive index :15 ° (C=3, MeOH)
storage temp. :-20°C
solubility :H2O: 50 mg/mL
form :powder
color :white to off-white
Water Solubility :almost transparency
BRN :3744166
InChIKey :QBNXAGZYLSRPJK-JEDNCBNOSA-N
CAS DataBase Reference :51298-62-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-NAME requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor (L-NNA). L-NNA exhibits some selectivity for inhibition of neuronal and endothelial isoforms. It exhibits Ki values of 15 nM, 39 nM, and 4.4 μM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively. The reported Ki value for the inhibition of iNOS ranges from 4-65 μM. L-NAME inhibits cGMP formation in endothelial cells with an IC50 of 3.1 μM (in the presence of 30 μM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC50 of 0.54 μM.

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