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ChemicalBook >> CAS DataBase List >> N-ACETYL-4-BENZOQUINONE IMINE

N-ACETYL-4-BENZOQUINONE IMINE

N-ACETYL-4-BENZOQUINONE IMINE price.
  • $117 - $1240
  • Product name: N-ACETYL-4-BENZOQUINONE IMINE
  • CAS: 50700-49-7
  • MF: C8H7NO2
  • MW: 149.15
  • EINECS:
  • MDL Number:MFCD00078909
  • Synonyms:N-ACETYLBENZOQUINONE-IMINE;N-N-Acetyl-4-benzoquinone Imine;N-ACETYL-PARA-QUINONEIMINE;N-Acetyl-p-benzoquinone imine (NAPQI), 98%;4-(Acetylimino)-2,5-cyclohexadien-1-one;N-(4-Oxo-1-cyclohexa-2,5-dienylidene)acetamide, N-Acetyl-p-benzo-quinone imine, NAPQI;N-Acetyl-1,4-benzoquinone imine;Chebi:29132
14 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 500μg
  • 1mg
  • 2mg
  • 0.005g
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAHH
  • Product numberMT-56285
  • Product descriptionN-Acetyl-4-benzoquinoneimine 95%
  • Packaging0.005g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1593BA
  • Product descriptionAcetimidoquinone
  • Packaging2mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17084
  • Product descriptionN-Acetyl-4-benzoquinone imine
  • Packaging1mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17084
  • Product descriptionN-Acetyl-4-benzoquinone imine
  • Packaging2mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17084
  • Product descriptionN-Acetyl-4-benzoquinone imine
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17084
  • Product descriptionN-Acetyl-4-benzoquinone imine
  • Packaging10mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17084
  • Product descriptionN-Acetyl-4-benzoquinone imine
  • Packaging25mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16115
  • Product descriptionN-Acetyl-4-benzoquinone imine ≥90%
  • Packaging500μg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16115
  • Product descriptionN-Acetyl-4-benzoquinone imine ≥90%
  • Packaging1mg
  • Price$222
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16115
  • Product descriptionN-Acetyl-4-benzoquinone imine ≥90%
  • Packaging5mg
  • Price$923
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA7300
  • Product descriptionN-Acetylbenzoquinoneimine
  • Packaging5mg
  • Price$1240
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA7300
  • Product descriptionN-Acetylbenzoquinoneimine
  • Packaging1mg
  • Price$315
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA170000
  • Product descriptionN-Acetyl-4-benzoquinoneImine
  • Packaging10mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberA0202-31
  • Product descriptionN-Acetyl-4-benzoquinone Imine
  • Packaging1mg
  • Price$446
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-56285 N-Acetyl-4-benzoquinoneimine 95% 0.005g $350 2021-12-16 Buy
AK Scientific 1593BA Acetimidoquinone 2mg $320 2021-12-16 Buy
Biosynth Carbosynth FA17084 N-Acetyl-4-benzoquinone imine 1mg $125 2021-12-16 Buy
Biosynth Carbosynth FA17084 N-Acetyl-4-benzoquinone imine 2mg $200 2021-12-16 Buy
Biosynth Carbosynth FA17084 N-Acetyl-4-benzoquinone imine 5mg $300 2021-12-16 Buy
Biosynth Carbosynth FA17084 N-Acetyl-4-benzoquinone imine 10mg $520 2021-12-16 Buy
Biosynth Carbosynth FA17084 N-Acetyl-4-benzoquinone imine 25mg $950 2021-12-16 Buy
Cayman Chemical 16115 N-Acetyl-4-benzoquinone imine ≥90% 500μg $117 2024-03-01 Buy
Cayman Chemical 16115 N-Acetyl-4-benzoquinone imine ≥90% 1mg $222 2024-03-01 Buy
Cayman Chemical 16115 N-Acetyl-4-benzoquinone imine ≥90% 5mg $923 2024-03-01 Buy
Sigma-Aldrich A7300 N-Acetylbenzoquinoneimine 5mg $1240 2024-03-01 Buy
Sigma-Aldrich A7300 N-Acetylbenzoquinoneimine 1mg $315 2024-03-01 Buy
TRC A170000 N-Acetyl-4-benzoquinoneImine 10mg $305 2021-12-16 Buy
Usbiological A0202-31 N-Acetyl-4-benzoquinone Imine 1mg $446 2021-12-16 Buy

Properties

Melting point :74-75
Boiling point :255.6±43.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-70°C
solubility :Chloroform (Slightly, Sonicated), DMSO (Slightly)
form :Solid
pka :-3.37±0.20(Predicted)
color :Pale Yellow to Very Dark Red
Stability :Temperature, Moisture, Light, and Oxygen Sensitive
CAS DataBase Reference :50700-49-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.