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ChemicalBook >> CAS DataBase List >> 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID

4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID price.
  • $31.6 - $3343.73
  • Product name: 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID
  • CAS: 39793-31-2
  • MF: C7H5NO2S
  • MW: 167.19
  • EINECS:
  • MDL Number:MFCD07368542
  • Synonyms:4H-thieno[3,2-b]pyrrole-5-carboxylic acid(SALTDATA: FREE);Thieno[2,3-b]pyrrole-5-carboxylic acid;4H-thieno[2,3-d]pyrrole-5-carboxylic acid;D-Amino Acid Oxidase Inhibitor;4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID;AKOS BB-9991;CHEMBRDG-BB 4012315;D-Amino Acid Oxidase Inhibitor - CAS 39793-31-2 - Calbiochem
24 prices
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Brand
  • Activate Scientific
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Atlantic Research Chemicals
  • Cayman Chemical
  • ChemBridge Corporation
  • Crysdot
  • Sigma-Aldrich
  • SynChem
  • TRC
Package
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
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  • 1gm:
  • ManufacturerActivate Scientific
  • Product numberAS148454
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97%
  • Packaging1g
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW6011
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
  • Packaging5g
  • Price$534
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50806
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
  • Packaging10g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50806
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
  • Packaging25g
  • Price$1285
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH58200
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97%
  • Packaging1g
  • Price$201.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH58200
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97%
  • Packaging5g
  • Price$770
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number39793312
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
  • Packaging1g
  • Price$194.93
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA823229
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97%
  • Packaging250mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA823229
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97%
  • Packaging1g
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA823229
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97%
  • Packaging5g
  • Price$449
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0025749
  • Product description4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID 95.00%
  • Packaging10G
  • Price$3343.73
  • Updated2021-12-16
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  • ManufacturerAtlantic Research Chemicals
  • Product numberCA100164
  • Product description4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 95%
  • Packaging1gm:
  • Price$168.25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23894
  • Product descriptionD-Amino Acid Oxidase Inhibitor ≥98%
  • Packaging250mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23894
  • Product descriptionD-Amino Acid Oxidase Inhibitor ≥98%
  • Packaging500mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23894
  • Product descriptionD-Amino Acid Oxidase Inhibitor ≥98%
  • Packaging1g
  • Price$241
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23894
  • Product descriptionD-Amino Acid Oxidase Inhibitor ≥98%
  • Packaging5g
  • Price$1002
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS148454 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 1g $184 2021-12-16 Buy
AK Scientific W6011 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 5g $534 2021-12-16 Buy
AK Scientific J50806 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 10g $700 2021-12-16 Buy
AK Scientific J50806 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 25g $1285 2021-12-16 Buy
Alfa Aesar H58200 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97% 1g $201.65 2024-03-01 Buy
Alfa Aesar H58200 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 97% 5g $770 2021-12-16 Buy
Alichem 39793312 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 1g $194.93 2021-12-16 Buy
Ambeed A823229 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 250mg $50 2021-12-16 Buy
Ambeed A823229 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 1g $129 2021-12-16 Buy
Ambeed A823229 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 97% 5g $449 2021-12-16 Buy
American Custom Chemicals Corporation CHM0025749 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID 95.00% 10G $3343.73 2021-12-16 Buy
Atlantic Research Chemicals CA100164 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid 95% 1gm: $168.25 2021-12-16 Buy
Cayman Chemical 23894 D-Amino Acid Oxidase Inhibitor ≥98% 250mg $68 2024-03-01 Buy
Cayman Chemical 23894 D-Amino Acid Oxidase Inhibitor ≥98% 500mg $130 2024-03-01 Buy
Cayman Chemical 23894 D-Amino Acid Oxidase Inhibitor ≥98% 1g $241 2024-03-01 Buy
Cayman Chemical 23894 D-Amino Acid Oxidase Inhibitor ≥98% 5g $1002 2024-03-01 Buy

Properties

Melting point :180 °C
Boiling point :437.4±25.0 °C(Predicted)
Density :1.609
storage temp. :Sealed in dry,2-8°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form :Beige solid
pka :4.36±0.30(Predicted)
color :Light brown to gray

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

D-Amino Acid Oxidase Inhibitor is a cell-permeable thienopyrrole compound that potently inhibits cellular activity of transfected D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) in CHO cells (IC50 against human and rat DAO = 145 and 114 nM, respectively). Exhibits no activity towards D-aspartate oxidase (DDO; IC50 >5 M), P450 enzymes CYP3A4/2D6/3C9 (IC50 >10 M), and a panel of over 150 other enzymes, receptors, and ion channels. Although treatment of Compound 8 (200 mg/kg, i.p.) is shown to effectively inhibit DAO activity in rat brain and kidney (by 96% and 80%, respectively), the resulting D-serine concentration increase in the periphery and central nervous system appears to be far from sufficient to produce adequate antipsychotic and cognitive enhancing effects.

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