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ChemicalBook >> CAS DataBase List >> 4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%

4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%

4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97% price.
  • $26 - $1000
  • Product name: 4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%
  • CAS: 349085-82-1
  • MF: C16H19NO3S
  • MW: 305.39
  • EINECS:
  • MDL Number:MFCD02007969
  • Synonyms:4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%;GSK137647A;GSK137647;4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide,97%;GSK137647A;GSK-137647A;GSK 137647A;GSK-137647;GSK 137647;GSK137647A, >98%;CS-2460;FFA4 (GPR120) agonist GS137647A
31 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 25mg
  • 50mg
  • 10mg
  • 50
  • 10
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5391
  • Product descriptionGSK137647A
  • Packaging100mg
  • Price$567
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH57808
  • Product description4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%
  • Packaging250mg
  • Price$80.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH57808
  • Product description4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97%
  • Packaging1g
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging1g
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging250mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging100mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging50mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging25mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging10mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA115691
  • Product descriptionGSK137647A 98+%
  • Packaging5mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026514
  • Product descriptionGSK-137647 95.00%
  • Packaging5MG
  • Price$501.88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7793
  • Product descriptionGSK137647
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17712
  • Product descriptionGSK137647A ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17712
  • Product descriptionGSK137647A ≥98%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17712
  • Product descriptionGSK137647A ≥98%
  • Packaging25mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17712
  • Product descriptionGSK137647A ≥98%
  • Packaging50mg
  • Price$419
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5391 GSK137647A 100mg $567 2021-12-16 Buy
Alfa Aesar H57808 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97% 250mg $80.6 2021-12-16 Buy
Alfa Aesar H57808 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide, 97% 1g $255 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 1g $312 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 250mg $125 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 100mg $84 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 50mg $57 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 25mg $44 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 10mg $34 2021-12-16 Buy
Ambeed A115691 GSK137647A 98+% 5mg $26 2021-12-16 Buy
American Custom Chemicals Corporation API0026514 GSK-137647 95.00% 5MG $501.88 2021-12-16 Buy
ApexBio Technology B7793 GSK137647 50mg $480 2021-12-16 Buy
Cayman Chemical 17712 GSK137647A ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 17712 GSK137647A ≥98% 10mg $109 2024-03-01 Buy
Cayman Chemical 17712 GSK137647A ≥98% 25mg $239 2024-03-01 Buy
Cayman Chemical 17712 GSK137647A ≥98% 50mg $419 2024-03-01 Buy

Properties

Boiling point :438.1±55.0 °C(Predicted)
Density :1.214±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol.
form :powder
pka :9.23±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :349085-82-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

GPR120 (Free Fatty Acid Receptor 4; FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. GSK137647A is a diarylsulfonamide that acts as a selective agonist of GPR120 (pEC50s = 6.3, 6.2, and 6.1 at human, mouse, and rat receptors, respectively). It is selective for GPR120 over a panel of 61 other targets, including other FFARs. Like the natural GPR120 ligand linoleic acid, GSK137647A dose-dependently stimulates insulin secretion by mouse insulinoma MIN6 cells under high glucose conditions. It also modestly stimulates the production of glucagon-like peptide-1 in taste bud cells and human intestinal NCI-H716 cells.