4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
![4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole price.](/CAS2/GIF/308357-81-5.gif)
|
- $85 - $1905.75
- Product name: 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- CAS: 308357-81-5
- MF: C36H61NO4S2Si2
- MW: 692.17
- EINECS:
- MDL Number:
- Synonyms:4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole;4-[(1E,3S,5Z,10S)-3,11-Bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-2,6,10-triMethyl-8-(phenylsulfonyl)-1,5-undecadi;Thiazole, 4-[(1E,3S,5Z,10S)-3,11-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6,10-trimethyl-8-(phenylsulfonyl)-1,5-undecadien-1-yl]-2-methyl-;Paclitaxel Impurity 74
11 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- TRC
Package
- 250mg
- 500MG
- 1g
- 2g
- 5G
- ManufacturerAK Scientific
- Product number8600DU
- Product description[(2S,9S)-4-(Benzenesulfonyl)-9-[tert-butyl(dimethyl)silyl]oxy-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienoxy]-tert-butyl-dimethylsilane
- Packaging1g
- Price$607
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001372
- Product description4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-8-(PHENYLSULFONYL)UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00%
- Packaging500MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001372
- Product description4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-8-(PHENYLSULFONYL)UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00%
- Packaging5G
- Price$1905.75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18798
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging250mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18798
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging500mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18798
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging1g
- Price$413
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18798
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging2g
- Price$750.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18798
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging5G
- Price$1365
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415850
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging1g
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415850
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging500mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415850
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging250mg
- Price$85
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8600DU | [(2S,9S)-4-(Benzenesulfonyl)-9-[tert-butyl(dimethyl)silyl]oxy-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienoxy]-tert-butyl-dimethylsilane | 1g | $607 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001372 | 4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-8-(PHENYLSULFONYL)UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00% | 500MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001372 | 4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-8-(PHENYLSULFONYL)UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00% | 5G | $1905.75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18798 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 250mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18798 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 500mg | $230 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18798 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 1g | $413 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18798 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 2g | $750.8 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18798 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 5G | $1365 | 2021-12-16 | Buy |
| TRC | B415850 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 1g | $250 | 2021-12-16 | Buy |
| TRC | B415850 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 500mg | $140 | 2021-12-16 | Buy |
| TRC | B415850 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-8-(phenylsulfonyl)undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 250mg | $85 | 2021-12-16 | Buy |
Properties
Boiling point :691.6±55.0 °C(Predicted)
Density :1.027±0.06 g/cm3(Predicted)
solubility :Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene
pka :2.72±0.10(Predicted)
form :Oil
color :Colourless
CAS DataBase Reference :308357-81-5
Density :1.027±0.06 g/cm3(Predicted)
solubility :Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene
pka :2.72±0.10(Predicted)
form :Oil
color :Colourless
CAS DataBase Reference :308357-81-5
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.More related product prices
(αR,βS)-β-[[(1,1-DiMethylethoxy)carbonyl]aMino]-α-hydroxy-4-(phenylMethoxy)-benzenepropanoic Acid Ethyl Ester 4-(BENZYLOXYCARBONYLAMINO-METHYL)-BENZOIC ACID Patupilone (4S,5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid 7-Xylosyl-10-deacetyltaxol 143527-70-2 (4S,5R)-2,2-DiMethyl-4-[4-(phenylMethoxy)phenyl]-N-DiMethylethoxycarbonyl-3,5-oxazolidinecarboxylic Acid Ethyl Ester Docetaxel-D9 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole DHA-paclitaxel (αR,βS)-(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-4-[(triethylsilyl)oxy]-benzeneprop 189453-10-9 Docetaxel Hydrate (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone 32981-85-4 (4S,5R)-2,2-DiMethyl-4-[4-(phenylMethoxy)phenyl]-3,5-oxazolidinedicarboxylic Acid 3-(1,1-DiMethylethyl) Ester 2-ethylpropane-1,3-diol 79839-49-9 Desbenzoyl Docetaxel (αR,βS)-β-(AcetylaMino)-α-hydroxy-4-(phenylMethoxy)-benzenepropanoic Acid Ethyl Ester