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ChemicalBook >> CAS DataBase List >> 25-hydroxycholesterol

25-hydroxycholesterol

25-hydroxycholesterol price.
  • $25 - $1871.1
  • Product name: 25-hydroxycholesterol
  • CAS: 2140-46-7
  • MF: C27H46O2
  • MW: 402.65
  • EINECS:
  • MDL Number:MFCD00057815
  • Synonyms:3BETA,25-DIHYDROXY-5-CHOLESTENE;5-CHOLESTEN-3-BETA, 25-DIOL;5-CHOLESTENE-3BETA,25-DIOL;25-Hydroxycholesterol (not deuterated);Cholest-5-ene-3,25-diol, (3.beta.)-;5-cholestene-3β,25-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;3β,25-Dihydroxycholest-5-ene
31 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50mg
  • 100mg
  • 250mg
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1865BA
  • Product description25-Hydroxycholesterol
  • Packaging1g
  • Price$1680
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging10mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging25mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging100mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA185451
  • Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
  • Packaging250mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0020768
  • Product description25-HYDROXYCHOLESTEROL 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0020768
  • Product description25-HYDROXYCHOLESTEROL 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11097
  • Product description25-hydroxy Cholesterol ≥98%
  • Packaging5mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11097
  • Product description25-hydroxy Cholesterol ≥98%
  • Packaging10mg
  • Price$48
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11097
  • Product description25-hydroxy Cholesterol ≥98%
  • Packaging25mg
  • Price$94
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11097
  • Product description25-hydroxy Cholesterol ≥98%
  • Packaging100mg
  • Price$350
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM201720
  • Product description25-Hydroxycholesterol 95%
  • Packaging100mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0061533
  • Product description25-Hydroxycholesterol ≥98.0%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0061533
  • Product description25-Hydroxycholesterol ≥98.0%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1865BA 25-Hydroxycholesterol 1g $1680 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 5mg $29 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 10mg $53 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 25mg $76 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 50mg $112 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 100mg $175 2021-12-16 Buy
Ambeed A185451 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% 250mg $288 2021-12-16 Buy
American Custom Chemicals Corporation LIP0020768 25-HYDROXYCHOLESTEROL 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation LIP0020768 25-HYDROXYCHOLESTEROL 95.00% 100MG $1871.1 2021-12-16 Buy
Cayman Chemical 11097 25-hydroxy Cholesterol ≥98% 5mg $25 2024-03-01 Buy
Cayman Chemical 11097 25-hydroxy Cholesterol ≥98% 10mg $48 2024-03-01 Buy
Cayman Chemical 11097 25-hydroxy Cholesterol ≥98% 25mg $94 2024-03-01 Buy
Cayman Chemical 11097 25-hydroxy Cholesterol ≥98% 100mg $350 2024-03-01 Buy
Chemenu CM201720 25-Hydroxycholesterol 95% 100mg $266 2021-12-16 Buy
ChemScene CS-0061533 25-Hydroxycholesterol ≥98.0% 5mg $50 2021-12-16 Buy
ChemScene CS-0061533 25-Hydroxycholesterol ≥98.0% 10mg $70 2021-12-16 Buy

Properties

Melting point :177-179 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
form :solid
pka :15.03±0.70(Predicted)
color :White or pale yellow
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

25-hydroxy Cholesterol is a side-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory element binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various cell types. It has been implicated in a variety of metabolic events including cholesterol homeostasis and atherosclerosis as well as antitumor activities as it has been shown to induce apoptosis through down-regulation of Bcl-2 expression and activation of caspases. Immunomodulating capabilities have also been observed as the oxysterol can act as a LXR-RXR ligand coupling cholesterol synthesis to T cell proliferation, can reduce (EC50 ~ 65 nM) IgA production by B cells in response to IL-2, and can suppress differentiation of monocytes into macrophages.

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