25-hydroxycholesterol
- $25 - $1871.1
- Product name: 25-hydroxycholesterol
- CAS: 2140-46-7
- MF: C27H46O2
- MW: 402.65
- EINECS:
- MDL Number:MFCD00057815
- Synonyms:3BETA,25-DIHYDROXY-5-CHOLESTENE;5-CHOLESTEN-3-BETA, 25-DIOL;5-CHOLESTENE-3BETA,25-DIOL;25-Hydroxycholesterol (not deuterated);Cholest-5-ene-3,25-diol, (3.beta.)-;5-cholestene-3β,25-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;3β,25-Dihydroxycholest-5-ene
31 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50mg
- 100mg
- 250mg
- 10
- 5mg
- 10mg
- 25mg
- 1g
- ManufacturerAK Scientific
- Product number1865BA
- Product description25-Hydroxycholesterol
- Packaging1g
- Price$1680
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging5mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging10mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging25mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging50mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging100mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging250mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020768
- Product description25-HYDROXYCHOLESTEROL 95.00%
- Packaging10MG
- Price$739.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020768
- Product description25-HYDROXYCHOLESTEROL 95.00%
- Packaging100MG
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11097
- Product description25-hydroxy Cholesterol ≥98%
- Packaging5mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11097
- Product description25-hydroxy Cholesterol ≥98%
- Packaging10mg
- Price$48
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11097
- Product description25-hydroxy Cholesterol ≥98%
- Packaging25mg
- Price$94
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11097
- Product description25-hydroxy Cholesterol ≥98%
- Packaging100mg
- Price$350
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM201720
- Product description25-Hydroxycholesterol 95%
- Packaging100mg
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0061533
- Product description25-Hydroxycholesterol ≥98.0%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0061533
- Product description25-Hydroxycholesterol ≥98.0%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1865BA | 25-Hydroxycholesterol | 1g | $1680 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 5mg | $29 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 10mg | $53 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 25mg | $76 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 50mg | $112 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 100mg | $175 | 2021-12-16 | Buy |
Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 250mg | $288 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | LIP0020768 | 25-HYDROXYCHOLESTEROL 95.00% | 10MG | $739.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | LIP0020768 | 25-HYDROXYCHOLESTEROL 95.00% | 100MG | $1871.1 | 2021-12-16 | Buy |
Cayman Chemical | 11097 | 25-hydroxy Cholesterol ≥98% | 5mg | $25 | 2024-03-01 | Buy |
Cayman Chemical | 11097 | 25-hydroxy Cholesterol ≥98% | 10mg | $48 | 2024-03-01 | Buy |
Cayman Chemical | 11097 | 25-hydroxy Cholesterol ≥98% | 25mg | $94 | 2024-03-01 | Buy |
Cayman Chemical | 11097 | 25-hydroxy Cholesterol ≥98% | 100mg | $350 | 2024-03-01 | Buy |
Chemenu | CM201720 | 25-Hydroxycholesterol 95% | 100mg | $266 | 2021-12-16 | Buy |
ChemScene | CS-0061533 | 25-Hydroxycholesterol ≥98.0% | 5mg | $50 | 2021-12-16 | Buy |
ChemScene | CS-0061533 | 25-Hydroxycholesterol ≥98.0% | 10mg | $70 | 2021-12-16 | Buy |
Properties
Melting point :177-179 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
form :solid
pka :15.03±0.70(Predicted)
color :White or pale yellow
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
form :solid
pka :15.03±0.70(Predicted)
color :White or pale yellow
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
25-hydroxy Cholesterol is a side-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory element binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various cell types. It has been implicated in a variety of metabolic events including cholesterol homeostasis and atherosclerosis as well as antitumor activities as it has been shown to induce apoptosis through down-regulation of Bcl-2 expression and activation of caspases. Immunomodulating capabilities have also been observed as the oxysterol can act as a LXR-RXR ligand coupling cholesterol synthesis to T cell proliferation, can reduce (EC50 ~ 65 nM) IgA production by B cells in response to IL-2, and can suppress differentiation of monocytes into macrophages.More related product prices
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Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.