2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE
- $50 - $1584
- Product name: 2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE
- CAS: 18080-67-6
- MF: C10H8Br2N2O2
- MW: 347.99
- EINECS:
- MDL Number:MFCD00186742
- Synonyms:2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE;2,3-bis(broMoMethyl)-1-oxoquinoxalin-1-iuM-4(1H)-olate;Conoidin A;Quinoxaline, 2,3-bis(bromomethyl)-, 1,4-dioxide;antioxidative,antioxidant,heart disease,Parasite,Inhibitor,Peroxiredoxin II,hyperperoxidation,Conoidin A,ischaemic,inhibit,neuroprotective
17 prices
Selected condition:
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5MG
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 25g
- ManufacturerAK Scientific
- Product number9480AA
- Product description2,3-Bis(bromomethyl)quinoxaline1,4-dioxide
- Packaging25mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number18080676
- Product description2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate
- Packaging5g
- Price$538.56
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number18080676
- Product description2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate
- Packaging25g
- Price$1584
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0362526
- Product description2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE 95.00%
- Packaging5MG
- Price$496.98
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidinA
- Packaging25mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidinA
- Packaging50mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidinA
- Packaging100mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidinA
- Packaging250mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15605
- Product descriptionConoidin A ≥98%
- Packaging25mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15605
- Product descriptionConoidin A ≥98%
- Packaging50mg
- Price$85
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15605
- Product descriptionConoidin A ≥98%
- Packaging100mg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15605
- Product descriptionConoidin A ≥98%
- Packaging250mg
- Price$249
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0063759
- Product descriptionConoidinA 98.03%
- Packaging25mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0063759
- Product descriptionConoidinA 98.03%
- Packaging100mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC43995
- Product descriptionConoidinA >98%
- Packaging1g
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number5.30746
- Product descriptionPeroxiredoxin Inhibitor, Conoidin A - CAS 18080-67-6 - Calbiochem
- Packaging25mg
- Price$264
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 9480AA | 2,3-Bis(bromomethyl)quinoxaline1,4-dioxide | 25mg | $160 | 2021-12-16 | Buy |
Alichem | 18080676 | 2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate | 5g | $538.56 | 2021-12-16 | Buy |
Alichem | 18080676 | 2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate | 25g | $1584 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0362526 | 2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE 95.00% | 5MG | $496.98 | 2021-12-16 | Buy |
ApexBio Technology | C4293 | ConoidinA | 25mg | $62 | 2021-12-16 | Buy |
ApexBio Technology | C4293 | ConoidinA | 50mg | $95 | 2021-12-16 | Buy |
ApexBio Technology | C4293 | ConoidinA | 100mg | $125 | 2021-12-16 | Buy |
ApexBio Technology | C4293 | ConoidinA | 250mg | $281 | 2021-12-16 | Buy |
Cayman Chemical | 15605 | Conoidin A ≥98% | 25mg | $57 | 2024-03-01 | Buy |
Cayman Chemical | 15605 | Conoidin A ≥98% | 50mg | $85 | 2024-03-01 | Buy |
Cayman Chemical | 15605 | Conoidin A ≥98% | 100mg | $111 | 2024-03-01 | Buy |
Cayman Chemical | 15605 | Conoidin A ≥98% | 250mg | $249 | 2024-03-01 | Buy |
ChemScene | CS-0063759 | ConoidinA 98.03% | 25mg | $50 | 2021-12-16 | Buy |
ChemScene | CS-0063759 | ConoidinA 98.03% | 100mg | $100 | 2021-12-16 | Buy |
DC Chemicals | DC43995 | ConoidinA >98% | 1g | $500 | 2021-12-16 | Buy |
Sigma-Aldrich | 5.30746 | Peroxiredoxin Inhibitor, Conoidin A - CAS 18080-67-6 - Calbiochem | 25mg | $264 | 2024-03-01 | Buy |
Properties
Melting point :180-190 °C (decomp)
Boiling point :512.3±60.0 °C(Predicted)
Density :1.95±0.1 g/cm3(Predicted)
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form :A crystalline solid
pka :1.91±0.30(Predicted)
color :White to yellow
Boiling point :512.3±60.0 °C(Predicted)
Density :1.95±0.1 g/cm3(Predicted)
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form :A crystalline solid
pka :1.91±0.30(Predicted)
color :White to yellow
Safety Information
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Description
Peroxiredoxins are a widely conserved family of enzymes that function in antioxidant defense and act in redox signaling pathways. Increased expression of human peroxiredoxin is associated with cancer, cardiovascular dysfunction, and neurodegeneration. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. At 5 μM, conoidin A can also inhibit the glucose oxidase-mediated hyperoxidation of mammalian peroxiredoxin I and II, but not peroxiredoxin III.Related product price
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