15-KETO LATANOPROST
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- $71 - $2194.5
- Product name: 15-KETO LATANOPROST
- CAS: 135646-98-9
- MF: C26H38O5
- MW: 430.58
- EINECS:
- MDL Number:MFCD03411998
- Synonyms:15-KETO LATANOPROST;9ALPHA,11ALPHA-DIHYDROXY-15-OXO-17-PHENYL-18,19,20-TRINOR-PROST-5Z-EN-1-OIC ACID ISOPROPYL ESTER;(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;[1R-[1α(Z),2β,3α,5α]]-7-[3,5-Dihydroxy-2-(3-oxo- 5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;Latanoprost Impurity 5;propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]hept-5-enoate;15-Keto Latanoprost/(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxo-5-phenylpentyl)cyclopentyl]-, 1-methylethyl ester, (5Z)-
8 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1MG
- 2.5MG
- 5mg
- 10mg
- 25MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010366
- Product description15-KETOLATANOPROST 95.00%
- Packaging1MG
- Price$213.15
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010366
- Product description15-KETOLATANOPROST 95.00%
- Packaging2.5MG
- Price$742.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010366
- Product description15-KETOLATANOPROST 95.00%
- Packaging25MG
- Price$2194.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16816
- Product description15-keto Latanoprost ≥98%
- Packaging10mg
- Price$599
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16816
- Product description15-keto Latanoprost ≥98%
- Packaging5mg
- Price$335
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16816
- Product description15-keto Latanoprost ≥98%
- Packaging1mg
- Price$71
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number51942
- Product description15-KetoLatanoprost
- Packaging1mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberK195350
- Product description15-KetoLatanoprost
- Packaging10mg
- Price$1620
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0010366 | 15-KETOLATANOPROST 95.00% | 1MG | $213.15 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010366 | 15-KETOLATANOPROST 95.00% | 2.5MG | $742.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010366 | 15-KETOLATANOPROST 95.00% | 25MG | $2194.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16816 | 15-keto Latanoprost ≥98% | 10mg | $599 | 2024-03-01 | Buy |
| Cayman Chemical | 16816 | 15-keto Latanoprost ≥98% | 5mg | $335 | 2024-03-01 | Buy |
| Cayman Chemical | 16816 | 15-keto Latanoprost ≥98% | 1mg | $71 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 51942 | 15-KetoLatanoprost | 1mg | $390 | 2021-12-16 | Buy |
| TRC | K195350 | 15-KetoLatanoprost | 10mg | $1620 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 100 mg/ml; DMSO: 100 mg/ml; DMSO:PBS (1:12): 80 μg/ml; Ethanol: 100 mg/ml
form :Oil to Thick Oil
color :Colourless
Stability :Hygroscopic
solubility :DMF: 100 mg/ml; DMSO: 100 mg/ml; DMSO:PBS (1:12): 80 μg/ml; Ethanol: 100 mg/ml
form :Oil to Thick Oil
color :Colourless
Stability :Hygroscopic
Safety Information
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Description
Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto latanoprost. 15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye. Products of β-oxidation account for most of the metabolites of latanoprost recovered in plasma and urine. However, 15-keto latanoprost is a minor metabolite, and one which could be enhanced in situations where β-oxidation is reduced.More related product prices
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