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ChemicalBook >> CAS DataBase List >> N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine

N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine

N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine price.
  • $86 - $1056
  • Product name: N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine
  • CAS: 1454585-06-8
  • MF: C23H19F3N8O
  • MW: 480.45
  • EINECS:-0
  • MDL Number:
  • Synonyms:N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine;SR-3029;N-[(6,7-Difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine;N-((6,7-Difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine;CS-2390;SR-3029 (SR 3029;SR-3029, >98%;9H-Purin-6-amine, N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-
18 prices
Selected condition：
Brand
  • AK Scientific
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 5
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number8653DP
  • Product descriptionN-[(4,5-Difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-morpholin-4-ylpurin-6-amine
  • Packaging10mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2547
  • Product descriptionSR3029 99%
  • Packaging5mg
  • Price$148.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27048
  • Product descriptionSR 3029
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27048
  • Product descriptionSR 3029
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27048
  • Product descriptionSR 3029
  • Packaging25mg
  • Price$258
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5672
  • Product descriptionSR-3029 99.58%
  • Packaging2mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5672
  • Product descriptionSR-3029 99.58%
  • Packaging5mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5672
  • Product descriptionSR-3029 99.58%
  • Packaging10mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5672
  • Product descriptionSR-3029 99.58%
  • Packaging25mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5672
  • Product descriptionSR-3029 99.58%
  • Packaging50mg
  • Price$1056
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003428
  • Product descriptionSR-3029 98+%
  • Packaging5mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003428
  • Product descriptionSR-3029 98+%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003428
  • Product descriptionSR-3029 98+%
  • Packaging25mg
  • Price$381
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003428
  • Product descriptionSR-3029 98+%
  • Packaging50mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9782
  • Product descriptionSR-3029 >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5767
  • Product descriptionSR3029 ≥98%(HPLC)
  • Packaging5
  • Price$224
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8653DP N-[(4,5-Difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-morpholin-4-ylpurin-6-amine 10mg $276 2021-12-16 Buy
Axon Medchem Axon2547 SR3029 99% 5mg $148.5 2021-12-16 Buy
Cayman Chemical 27048 SR 3029 5mg $86 2024-03-01 Buy
Cayman Chemical 27048 SR 3029 10mg $161 2024-03-01 Buy
Cayman Chemical 27048 SR 3029 25mg $258 2024-03-01 Buy
ChemScene CS-5672 SR-3029 99.58% 2mg $120 2021-12-16 Buy
ChemScene CS-5672 SR-3029 99.58% 5mg $192 2021-12-16 Buy
ChemScene CS-5672 SR-3029 99.58% 10mg $312 2021-12-16 Buy
ChemScene CS-5672 SR-3029 99.58% 25mg $660 2021-12-16 Buy
ChemScene CS-5672 SR-3029 99.58% 50mg $1056 2021-12-16 Buy
Crysdot CD31003428 SR-3029 98+% 5mg $111 2021-12-16 Buy
Crysdot CD31003428 SR-3029 98+% 10mg $180 2021-12-16 Buy
Crysdot CD31003428 SR-3029 98+% 25mg $381 2021-12-16 Buy
Crysdot CD31003428 SR-3029 98+% 50mg $610 2021-12-16 Buy
DC Chemicals DC9782 SR-3029 >98% 250mg $950 2021-12-16 Buy
Tocris 5767 SR3029 ≥98%(HPLC) 5 $224 2021-12-16 Buy

Properties

Boiling point :818.7±75.0 °C(Predicted)
Density :1.62±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml
form :A solid
pka :8.76±0.30(Predicted)
color :White to pink

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

SR-3029 is a potent and selective CK1δ and CK1ε inhibitor (IC50 values are 44 and 260 nM, respectively). Exhibits selectivity for CK1δ and CK1ε over a panel of other kinases. Inhibits proliferation of melanoma and breast cancer cell lines in vitro. Also inhibits growth of breast tumor xenografts in mice.

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