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ChemicalBook >> CAS DataBase List >> Dexmedetomidine hydrochloride

Dexmedetomidine hydrochloride

Dexmedetomidine hydrochloride price.
  • $25 - $1504.5
  • Product name: Dexmedetomidine hydrochloride
  • CAS: 145108-58-3
  • MF: C13H17ClN2
  • MW: 236.74
  • EINECS:682-047-2
  • MDL Number:MFCD07772269
  • Synonyms:4-((S)-α,2,3-Trimethylbenzyl)imidazole monohydrochloride;DeMedetoMidine hydrochloride;(S)-4-(1-(2,3-diMethylphenyl)ethyl)-1H-iMidazole hydrochloride;1H-IMidazole,5-[(1S)-1-(2,3-diMethylphenyl)ethyl]-, hydrochloride (1:1);5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole,hydrochloride (1:1);Dexmedetomidine hydrochloride 4-((S)-alpha,2,3-Trimethylbenzyl)imidazole monohydrochloride;(S)-Medetomidine hydrochloride;Given dexmedetomidine hydrochloride
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  • Adipogen Life Sciences
  • AK Scientific
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  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0792-M010
  • Product descriptionDexmedetomidine Hydrochloride ≥98%(HPLC)
  • Packaging10mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0792-M050
  • Product descriptionDexmedetomidine Hydrochloride ≥98%(HPLC)
  • Packaging50mg
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF355
  • Product descriptionDexmedetomidineHCl
  • Packaging100mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging5mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging5mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging10mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging10mg
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging100mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging25mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging1g
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging1g
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging25mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging250mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging50mg
  • Price$93
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA184218
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+%
  • Packaging50mg
  • Price$93
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1490738
  • Product description(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95%
  • Packaging100mg
  • Price$120
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-D0792-M010 Dexmedetomidine Hydrochloride ≥98%(HPLC) 10mg $53 2021-12-16 Buy
Adipogen Life Sciences CDX-D0792-M050 Dexmedetomidine Hydrochloride ≥98%(HPLC) 50mg $212 2021-12-16 Buy
AK Scientific F355 DexmedetomidineHCl 100mg $138 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 5mg $25 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 5mg $25 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 10mg $36 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 10mg $36 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 100mg $47 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 25mg $64 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 1g $462 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 1g $462 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 25mg $64 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 250mg $69 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 50mg $93 2021-12-16 Buy
Ambeed A184218 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 99+% 50mg $93 2021-12-16 Buy
Ambeed A1490738 (S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazolehydrochloride 95% 100mg $120 2021-12-16 Buy

Properties

Melting point :156.5-157.5°
alpha :+52.4° (c = 1 in water)
Density :1.17 g/cm3
storage temp. :2-8°C
solubility :H2O: soluble20mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D +48 to +58°, c = 1 in H2O
Merck :14,2946
Stability :Hygroscopic
InChI :InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/s3
InChIKey :VPNGEIHDPSLNMU-MERQFXBCSA-N
SMILES :[C@@H](C1NC=NC=1)(C1C=CC=C(C)C=1C)C.Cl |&1:0,r|
CAS DataBase Reference :145108-58-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dexmedetomidine is the (S)-enantiomer of medetomidine, an imidazole compound that binds to α2-adrenoceptors (Ki = 1.08 nM) with high affinity and selectivity compared to that of α1-adrenoceptors (Ki = 1.8 μM). Dexmedetomidine produces analgesic, sedative, and anxiolytic effects through both presynaptic activation of α2-adrenoceptors, which inhibits norepinephrine release, and postsynaptic activation of α2-adrenoceptors, which inhibits sympathetic activity and decreases blood pressure and heart rate.

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