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ChemicalBook >> CAS DataBase List >> [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone price.
  • $37 - $931
  • Product name: [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone
  • CAS: 1382481-79-9
  • MF: C22H23NO3
  • MW: 349.42
  • EINECS:802-823-8
  • MDL Number:MFCD25541754
  • Synonyms:[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone;ML289;VU0463597;[(3R)-3-(hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;[(3R)-3-(Hydroxymethyl)-1-pipridinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;Methanone, [(3R)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-;(3R)-3-(Hydroxymethyl)-1-piperidinyl]{4-[(4-methoxyphenyl)ethyny l]phenyl}methanone
13 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number7624DM
  • Product description[(3R)-3-(Hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5346
  • Product descriptionML289
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5346
  • Product descriptionML289
  • Packaging100mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5783
  • Product descriptionML289
  • Packaging10mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15195
  • Product descriptionML-289 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15195
  • Product descriptionML-289 ≥98%
  • Packaging5mg
  • Price$90
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15195
  • Product descriptionML-289 ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15195
  • Product descriptionML-289 ≥98%
  • Packaging25mg
  • Price$353
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0555
  • Product descriptionML289 ≥98% (HPLC)
  • Packaging25mg
  • Price$392
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number4976
  • Product descriptionML289 ≥98%(HPLC)
  • Packaging10
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4976
  • Product descriptionML289 ≥98%(HPLC)
  • Packaging50
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM425325
  • Product descriptionML-289
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255860
  • Product descriptionML 289
  • Packaging10mg
  • Price$452
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7624DM [(3R)-3-(Hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone 1mg $139 2021-12-16 Buy
AK Scientific SYN5346 ML289 10mg $160 2021-12-16 Buy
AK Scientific SYN5346 ML289 100mg $931 2021-12-16 Buy
ApexBio Technology B5783 ML289 10mg $245 2021-12-16 Buy
Cayman Chemical 15195 ML-289 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 15195 ML-289 ≥98% 5mg $90 2024-03-01 Buy
Cayman Chemical 15195 ML-289 ≥98% 10mg $161 2024-03-01 Buy
Cayman Chemical 15195 ML-289 ≥98% 25mg $353 2024-03-01 Buy
Sigma-Aldrich SML0555 ML289 ≥98% (HPLC) 25mg $392 2022-05-15 Buy
Tocris 4976 ML289 ≥98%(HPLC) 10 $109 2021-12-16 Buy
Tocris 4976 ML289 ≥98%(HPLC) 50 $459 2021-12-16 Buy
TRC M425325 ML-289 5mg $65 2021-12-16 Buy
Usbiological 255860 ML 289 10mg $452 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites within the receptor are being developed to preferentially target individual mGluR subtypes in order to determine their distinct pharmacological roles. ML-298 is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.

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