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ChemicalBook >> CAS DataBase List >> H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH

H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH price.
  • $459 - $5263.2
  • Product name: H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
  • CAS: 136461-80-8
  • MF: C269H381N67O82S2
  • MW: 5929.43
  • EINECS:
  • MDL Number:MFCD00147801
  • Synonyms:TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL (DISULFIDE BRIDGE: CYS23-CYS29);TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL: YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFY;YLYQWLGAPVPYPDPL-Gla-PRR-Gla-VC-Gla-LNPDCDELADHIGFQEAYRRFYGPV(Gla=γ-CarboxyglutamicAcid:Disulfidebridge:23-29);Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Arg-Arg-Gla-Val-Cys-Gla-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val(Disu;OSTEOCALCIN (HUMAN, GLA17,21,24);OSTEOCALCIN (1-49) (HUMAN);TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL;YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV
7 prices
Selected condition：
Brand
  • Biorbyt Ltd
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 100μg
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerBiorbyt Ltd
  • Product numberorb372957
  • Product descriptionOsteocalcin (1-49) > 95%
  • Packaging10mg
  • Price$5263.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb372957
  • Product descriptionOsteocalcin (1-49) > 95%
  • Packaging5mg
  • Price$3512.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb372957
  • Product descriptionOsteocalcin (1-49) > 95%
  • Packaging1mg
  • Price$1412.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24723
  • Product descriptionOsteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%
  • Packaging100μg
  • Price$459
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24723
  • Product descriptionOsteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%
  • Packaging500μg
  • Price$1148
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO5761
  • Product descriptionOsteocalcin fragment 1-49 Human ≥94% (HPLC), solid
  • Packaging1mg
  • Price$1640
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO5761
  • Product descriptionOsteocalcin fragment 1-49 Human ≥94%(HPLC),solid
  • Packaging500μg
  • Price$852
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Biorbyt Ltd orb372957 Osteocalcin (1-49) > 95% 10mg $5263.2 2021-12-16 Buy
Biorbyt Ltd orb372957 Osteocalcin (1-49) > 95% 5mg $3512.2 2021-12-16 Buy
Biorbyt Ltd orb372957 Osteocalcin (1-49) > 95% 1mg $1412.7 2021-12-16 Buy
Cayman Chemical 24723 Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95% 100μg $459 2024-03-01 Buy
Cayman Chemical 24723 Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95% 500μg $1148 2024-03-01 Buy
Sigma-Aldrich O5761 Osteocalcin fragment 1-49 Human ≥94% (HPLC), solid 1mg $1640 2024-03-01 Buy
Sigma-Aldrich O5761 Osteocalcin fragment 1-49 Human ≥94%(HPLC),solid 500μg $852 2024-03-01 Buy

Properties

storage temp. :-20°C
solubility :Formic Acid: 1 mg/ml
form :solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget''s disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.