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ChemicalBook >> CAS DataBase List >> tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate price.
  • $220 - $3098
  • Product name: tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
  • CAS: 1201187-44-1
  • MF: C18H20N4O4S
  • MW: 388.44
  • EINECS:
  • MDL Number:MFCD28129728
  • Synonyms:tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate;Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester;tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate;Intermediate of Upadacitinib (ABT-494);2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate;Upadacitinib intermediate2;2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...
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Brand
  • Chemenu
  • Crysdot
  • TRC
Package
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerChemenu
  • Product numberCM119289
  • Product description2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+
  • Packaging1g
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM119289
  • Product description2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+
  • Packaging5g
  • Price$858
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM119289
  • Product description2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+
  • Packaging10g
  • Price$1788
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM119289
  • Product description2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+
  • Packaging25g
  • Price$3098
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11333434
  • Product descriptiontert-Butyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate 97%
  • Packaging1g
  • Price$1085
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB809575
  • Product descriptiontert-ButylN-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate
  • Packaging250mg
  • Price$220
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 1g $310 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 5g $858 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 10g $1788 2021-12-16 Buy
Chemenu CM119289 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine 95%+ 25g $3098 2021-12-16 Buy
Crysdot CD11333434 tert-Butyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate 97% 1g $1085 2021-12-16 Buy
TRC B809575 tert-ButylN-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate 250mg $220 2021-12-16 Buy

Properties

Density :1.35±0.1 g/cm3(Predicted)
pka :9.45±0.43(Predicted)
InChI :InChI=1S/C18H20N4O4S/c1-12-5-7-13(8-6-12)27(24,25)22-10-9-14-16(22)19-11-15(20-14)21-17(23)26-18(2,3)4/h5-11H,1-4H3,(H,20,21,23)
InChIKey :NTMJGYRFMXFNIC-UHFFFAOYSA-N
SMILES :C(OC(C)(C)C)(=O)NC1=CN=C2N(S(C3=CC=C(C)C=C3)(=O)=O)C=CC2=N1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.

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