Methanol
Product identifier
- Product name: Methanol
- CBnumber: CB7854099
- CAS: 67-56-1
- EINECS Number: 200-659-6
- Synonyms: Methanol,jiachun
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Methanol
- Synonyms: Methanol,jiachun
- CAS: 67-56-1
- EC number: 200-659-6
- MF: CH4O
- MW: 32.04
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 120 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
Flame retardant antistatic protective clothing.
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odourcharacteristic
- Odour Threshold10 ppm
- pHNo data available
- Melting point/freezing pointMelting point/range: -98 °C
- Initial boiling point and boiling range64,7 °C
- Flash point9,7 °C - closed cup - Regulation (EC) No. 440/2008, Annex, A.9
- Evaporation rate6,3 - Diethyl ether1,9 - n-butyl acetate
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 44 %(V) Lower explosion limit: 5,5 %(V)
- Vapour pressure 169,27 hPa at 25 °C
- Vapour density 1,11
- Relative density0,791 g/mL at 25 °C 0,79 - 0,8 at 20 °C
- Water solubility1.000 g/l at 20 °C - completely miscibleat 20 °C soluble
- Partition coefficient: n-octanol/waterlog Pow: -0,77 - (Lit.), Bioaccumulation is not expected.
- Autoignition temperature455,0 °C at 1.013 hPa - DIN 51794
- Decomposition temperatureDistillable in an undecomposed state at normal pressure.
- ViscosityViscosity, kinematic: 0,54 - 0,59 mm2/s at 20 °C Viscosity, dynamic: >0,544 -< 0,59 mPa.s at 25 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant4.99 at 25 °C (headspace-GC, Gupta et al., 2000)
- λmaxλ: 210 nm Amax: 0.50
λ: 220 nm Amax: 0.30
λ: 230 nm Amax: 0.15
λ: 235 nm Amax: 0.10
λ: 240 nm Amax: 0.05
λ: 260 nm Amax: 0.01
λ: 400 nm Amax: 0.01
Other safety information
Minimum ignition energy
0,14 mJ
Conductivity < 1 μS/cm
Relative vapor density
1,11
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Risk of explosion with: Oxidizing agents perchloric acid perchlorates
salts of oxyhalogenic acids chromium(VI) oxide halogen oxides
nitrogen oxides nonmetallic oxides
chromosulfuric acid chlorates
hydrides zinc diethyl halogens
powdered magnesium hydrogen peroxide Nitric acid
sulfuric acid permanganic acid sodium hypochlorite
Exothermic reaction with:
acid halides Acid anhydrides Reducing agents acids
Bromine Chlorine Chloroform magnesium
tetrachloromethane
Risk of ignition or formation of inflammable gases or vapours with: Fluorine
Oxides of phosphorus Raney-nickel
Generates dangerous gases or fumes in contact with: Alkaline earth metals
Alkali metals
Conditions to avoid
Warming.
Incompatible materials
various plastics, magnesium, zinc alloys
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityAcute toxicity estimate Oral - 100,1 mg/kg (Expert judgment)
Symptoms: Nausea, Vomiting
Acute toxicity estimate Inhalation - 4 h - 3,1 mg/l (Expert judgment)
Acute toxicity estimate Inhalation - 4 h - 3,1 mg/l (Expert judgment)
Symptoms: Irritation symptoms in the respiratory tract.
Acute toxicity estimate Dermal - 300,1 mg/kg (Expert judgment)
Acute toxicity estimate Dermal - 300,1 mg/kg (Expert judgment)
Result: No skin irritation Remarks: (ECHA)
Drying-out effect resulting in rough and chapped skin.
Result: No eye irritation Remarks: (ECHA)
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test Species: Mouse
Cell type: Bone marrow
Application Route: Intraperitoneal injection Method: OECD Test Guideline 474
Result: negative
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
5628 mg/kg
LD50 skin (rabbit)
15,840 mg/kg
LC50 inhal (rat)
>145,000 ppm (1 h)
PEL (OSHA)
200 ppm (260 mg/m3)
TLV-TWA (ACGIH)
200 ppm (260 mg/m3)—skin
STEL (ACGIH)
250 ppm (328 mg/m3)
Toxicity
(US-EPA)
semi-static test EC50 - Daphnia magna (Water flea) - 18.260 mg/l - 96 h
(OECD Test Guideline 202)
22.000,0 mg/l - 96 h (OECD Test Guideline 201)
Persistence and degradability
Biodegradability Result: 99 % - Readily biodegradable.
(OECD Test Guideline 301D)
Biochemical Oxygen Demand (BOD)
Chemical Oxygen Demand (COD)
Theoretical oxygen demand
600 - 1.120 mg/g Remarks: (IUCLID)
1.420 mg/g Remarks: (IUCLID)
1.500 mg/g Remarks: (Lit.)
Ratio BOD/ThBOD 76 %
Remarks: Closed Bottle test(IUCLID)
Bioaccumulative potential
Bioaccumulation Cyprinus carpio (Carp) - 72 d
at 20 °C - 5 mg/l(Methanol)
Bioconcentration factor (BCF): 1,0
Mobility in soil
Will not adsorb on soil.
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological information
Avoid release to the environment.
Stability in water at 19 °C83 - 91 % - 72 h
Remarks: Hydrolyzes on contact with water.Hydrolyzes readily.
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesMethanol reacts violently with strong oxidizers, causing a fire and explosion hazard.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal. Incineration
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 3 (6.1) IMDG: 3 (6.1) IATA: 3 (6.1)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.