5-Nitrobenzimidazole
Product identifier
- Product name: 5-Nitrobenzimidazole
- CBnumber: CB8697293
- CAS: 94-52-0
- EINECS Number: 202-341-2
- Synonyms: 5-nitro-1H-benzo[d]imidazole,5-Nitrobenzimidazole
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Label elements
Pictogram(s)
- Signal wordWarning
H351 Suspected of causing cancer
H402 Harmful to aquatic life
H412 Harmful to aquatic life with long lasting effects
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 5-Nitrobenzimidazole
- Synonyms: 5-nitro-1H-benzo[d]imidazole,5-Nitrobenzimidazole
- CAS: 94-52-0
- EC number: 202-341-2
- MF: C7H5N3O2
- MW: 163.13
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
SYMPTOMS: Exposure to this chemical can cause irritation. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of carbon monoxide, carbon dioxide and NOx. This chemical is harmful by inhalation, ingestion, or skin absorption. (NTP, 1992)
Indication of any immediate medical attention and special treatment needed
no data available
Extinguishing media
Fires involving this compound should be controlled with a dry chemical, carbon dioxide, or Halon extinguisher. (NTP, 1992)
Specific Hazards Arising from the Chemical
Flash point data for this chemical are not available but it is probably combustible. (NTP, 1992)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical stateSolid
- ColourLight Beige
- Odour
no data available
- Melting point/freezing point
285°C(dec.)(lit.)
- Boiling point or initial boiling point and boiling range
117°C/4mmHg(lit.)
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
42°C(lit.)
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH6 (10g/l, H2O, 20℃)(slurry)
- Kinematic viscosity
no data available
- Solubility0.5g/l
- Partition coefficient n-octanol/water
no data available
- Vapour pressure
no data available
- Density and/or relative density
1.525 g/cm3
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
6-NITROBENZIMIDAZOLE is incompatible with strong oxidizing agents and strong bases. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: 5-Nitrobenzimidazole, present at 100 mg/l, reached 0% of its theoretical BOD in 6 weeks using an activated sludge inoculum at 30 mg/l and the Japanese MITI test(1).
Bioaccumulative potential
BCFs of 0.7-1.8 were measured for 5-nitrobenzimidazole(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low.
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc for 5-nitrobenzimidazole can be estimated to be 120(SRC). According to a classification scheme(2), this estimated Koc value suggests that 5-nitrobenzimidazole is expected to have high mobility in soil. 5-Nitrobenzimidazole is predicted(3) to have two environmentally relevant pKa's, one at 3.7 and the other at 10.7, corresponding to the protonation and deprotonation of one of the nitrogens in the imidazole structure, respectively. Therefore, under neutral environmental conditions, 5-nitrobenzimidazole will exist in the uncharged form. At low pH, some 5-nitrobenzimidazole will be cationic, and in this form will be more likely to sorptive to soil particles.
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN3152 (For reference only, please check.)
IMDG: UN3152 (For reference only, please check.)
IATA: UN3152 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: POLYHALOGENATED BIPHENYLS, SOLID or HALOGENATED MONOMETHYLDIPHENYL- METHANES, SOLID or POLYHALOGENATED TERPHENYLS, SOLID (For reference only, please check.)
IMDG: POLYHALOGENATED BIPHENYLS, SOLID or HALOGENATED MONOMETHYLDIPHENYL- METHANES, SOLID or POLYHALOGENATED TERPHENYLS, SOLID (For reference only, please check.)
IATA: POLYHALOGENATED BIPHENYLS, SOLID or HALOGENATED MONOMETHYLDIPHENYL- METHANES, SOLID or POLYHALOGENATED TERPHENYLS, SOLID (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.