4,4'-Thiobis(6-tert-butyl-m-cresol)
Product identifier
- Product name: 4,4'-Thiobis(6-tert-butyl-m-cresol)
- CBnumber: CB0722795
- CAS: 96-69-5
- EINECS Number: 202-525-2
- Synonyms: Antioxidant 300,4,4'-Thiobis(6-tert-butyl-m-cresol)
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Label elements
Pictogram(s)
- Signal wordWarning
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H373 May cause damage to organs through prolonged or repeated exposure
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 4,4'-Thiobis(6-tert-butyl-m-cresol)
- Synonyms: Antioxidant 300,4,4'-Thiobis(6-tert-butyl-m-cresol)
- CAS: 96-69-5
- EC number: 202-525-2
- MF: C22H30O2S
- MW: 358.54
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin, respiratory system Target Organs: Eyes, skin, respiratory system (NIOSH, 2016)
Indication of any immediate medical attention and special treatment needed
no data available
Extinguishing media
Fires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Specific Hazards Arising from the Chemical
This chemical is combustible. (NTP, 1992)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
Control parameters
Occupational Exposure limit values| Component | 6,6'-di-tert-butyl-4,4'-thiodi-m-cresol | |||
|---|---|---|---|---|
| CAS No. | 96-69-5 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Australia | ? | 10 | ? | ? |
| Belgium | ? | 10 | ? | ? |
| Canada - Ontario | ? | 1 (1) | ? | ? |
| Canada - Québec | ? | 10 | ? | ? |
| Denmark | ? | 10 | ? | 20 |
| France | ? | 10 | ? | ? |
| Ireland | ? | 10 | ? | ? |
| New Zealand | ? | 10 | ? | ? |
| Singapore | ? | 10 | ? | ? |
| South Korea | ? | 10 | ? | ? |
| Spain | ? | 10 | ? | ? |
| Switzerland | ? | 10 inhalable aerosol | ? | ? |
| USA - NIOSH | ? | 10 total dust | ? | ? |
| ? | ? | 5 respirable fraction | ? | ? |
| USA - OSHA | ? | 15 inhalable aerosol | ? | ? |
| ? | ? | 5 respirable aerosol | ? | ? |
| United Kingdom | ? | 10 | ? | 20 |
| Remarks | ||||
| Canada - Ontario | (1) Inhalable fraction. | |||
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical stateFine white to gray powder.
- ColourWhite to Off-White
- Odour
Slightly aromatic odor.
- Melting point/freezing point
162 °C. Atm. press.:1 016 hPa.
- Boiling point or initial boiling point and boiling range
378 °C. Atm. press.:1 016 hPa.
- Flammability
Combustible Solid
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
109°C(lit.)
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- SolubilityDMSO (Slightly), Methanol (Slightly)
- Partition coefficient n-octanol/water
log Pow = 5.24. Temperature:25 °C. Remarks:In the chromatogram of the test solution, one test substance peak was observed.
- Vapour pressure
< 0.001 Pa. Temperature:20 °C.
- Density and/or relative density
1.11 g/cm3. Temperature:20 °C.;1.11. Temperature:20 °C.
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
Sensitive to base hydrolysis and may spontaneously oxidize in solution. (NTP, 1992). Insoluble in water.
Chemical stability
no data available
Possibility of hazardous reactions
4,4'-THIOBIS(6-TERT-BUTYL-M-CRESOL) may be sensitive to light.
Conditions to avoid
no data available
Incompatible materials
STABILITY: This chemical may be sensitive to light. It is sensitive to base hydrolysis and may spontaneously oxidize in solution. (NTP, 1992)
Hazardous decomposition products
no data available
Acute toxicity
- Oral: LD50 - rat (male/female) - 4 150 mg/kg bw.
- Inhalation: no data available
- Dermal: LD50 - rabbit (male/female) - > 5 010 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Carcinogenicity
A4; Not classifiable as a human carcinogen. 4,4-Thiobis(6-tert-butyl-m-cresol)
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 0.36 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.16 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 90 mg/L - 96 h.
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.