2-Methoxyethanol
Product identifier
- Product name: 2-Methoxyethanol
- CBnumber: CB4852791
- CAS: 109-86-4
- EINECS Number: 231-791-2
- Synonyms: h2o,2-methoxyethanol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: 2-Methoxyethanol
- Synonyms: h2o,2-methoxyethanol
- CAS: 109-86-4
- EC number: 231-791-2
- MF: C3H8O2
- MW: 76.09
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject? (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Viton?
Minimum layer thickness: 0,7 mm Break through time: 120 min
Material tested:Vitoject? (KCL 890 / Aldrich Z677698, Size M)
Flame retardant antistatic protective clothing.
Recommended Filter type: Filter A-(P2)
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearancecolorless clear, liquid
- Odourether-like
- Odour Threshold2,3 ppm d) pH 5,0 - 7,0 at 25 °C Melting point/freezing point Initial boiling point and boiling range Melting point/range: -85 °C - lit. 124 - 125 °C - lit. Flash point 40 °C - closed cup Evaporation rate No data available Flammability (solid, gas) Upper/lower flammability or explosive limits No data available Upper explosion limit: 24,5 %(V) Lower explosion limit: 2,5 %(V) Vapour pressure 10 hPa at 20 °C Vapour density 2,63 - (Air = 1.0) Density 0,965 g/cm3 at 25 °C - lit. Relative density No data available Water solubility at 20 °C soluble Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: -0,77 at 28 °C - Bioaccumulation is not expected., (Lit.) No data available 204 - 232 °C - Viscosity Viscosity, kinematic: 1,6 mm2/s at 20 °C Viscosity, dynamic: 1,7 mPa.s at 20 °C Explosive properties No data available Oxidizing properties No data available
- Melting point/freezing pointMelting point/range: -85 °C - lit.
- Initial boiling point and boiling range124 - 125 °C - lit.
- Flash point40 °C - closed cup
- Evaporation rate115 °F
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 24,5 %(V) Lower explosion limit: 2,5 %(V)
- Vapour pressure 10 hPa at 20 °C
- Vapour density 2,63 - (Air = 1.0)
- Relative density2.62 (vs air)
- Water solubilityat 20 °C soluble
- Partition coefficient: n-octanol/waterlog Pow: -0,77 at 28 °C - Bioaccumulation is not expected., (Lit.)
- Autoignition temperatureNo data available
- Decomposition temperature 204 - 232 °C -
- ViscosityViscosity, kinematic: 1,6 mm2/s at 20 °C Viscosity, dynamic: 1,7 mPa.s at 20 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- Henry's Law Constant(x 10-2 atm?m3/mol): 4.41, 3.63, 11.6, 3.09, and 3.813 at 10, 15, 20, 25, and 30 °C, respectively (EPICS, Ashworth et al., 1988)
- λmaxλ: 213 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01
Other safety information
Surface tension ca.72 mN/m at 25 °C
Relative vapor density
2,63 - (Air = 1.0)
Reactivity
Vapors may form explosive mixture with air. Vapor/air-mixtures are explosive at intense warming.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Generates dangerous gases or fumes in contact with:
Aluminum magnesium bases
Zinc
Risk of explosion with:
Oxidizing agents Air
Possible formation of:
Peroxides
Conditions to avoid
Heat. 45°C Heating.
Incompatible materials
Aluminum, various plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: Behavioral:General anesthetic. Blood:Other hemolysis with or withot anemia. (RTECS)
Symptoms: Risk of aspiration upon vomiting., Aspiration may cause pulmonary edema and pneumonitis.
Acute toxicity estimate Inhalation - Expert judgment - 4 h - 11 mg/l LD50 Dermal - Rabbit - 1.280 mg/kg
Remarks: (RTECS)
Result: No skin irritation - 4 h (Directive 67/548/EEC, Annex V, B.4.)
Result: slight irritation
(OECD Test Guideline 405)
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Chromosome aberration test Species: Mouse
Application Route: Oral
Method: OECD Test Guideline 475 Result: negative
Toxicity
(OECD Test Guideline 203)
semi-static test EC50 - Daphnia magna (Water flea) - 27.000 mg/l - 48 h
(ISO 6341)
25.500 mg/l - 72 h (ISO 8692)
Persistence and degradability
Biodegradability aerobic - Exposure time 20 d
Result: 88 % - Readily biodegradable. Remarks: (ECHA)
Bioaccumulative potential
No bioaccumulation is to be expected (log Pow <= 4).
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
IncompatibilitiesVapors may form explosive mixture with air. Heat or oxidizers may cause the formation of unstable peroxides. Attacks many metals. Strong oxidizers may cause fire and explosions. Strong bases cause decomposition and the formation of toxic gas. Attacks some plastics, rubber and coatings. May accumulate static electrical charges, and may cause ignition of its vapors.
Waste DisposalConcentrated waste containing no peroxides: discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxides: perforation of a container of the waste from a safe distance followed by open burning.
UN number
ADR/RID: 1188 IMDG: 1188 IATA: 1188
UN proper shipping name
| | ADR/RID: ETHYLENE GLYCOL MONOMETHYL ETHER IMDG: ETHYLENE GLYCOL MONOMETHYL ETHER | |
| IATA: Ethylene glycol monomethyl ether | ||
| 14.3 | Transport hazard class(es) ADR/RID: 3 IMDG: 3 | IATA: 3 |
| 14.4 | Packaging group ADR/RID: III IMDG: III | IATA: III |
| 14.5 | Environmental hazards ADR/RID: yes IMDG Marine pollutant: yes | IATA: no |
| 14.6 | Special precautions for user No data available | |
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.