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Kisspeptin 10 (rat)

Release time: 2024-06-24

Product Description

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What is kisspeptin 10 used for?
Kisspeptin plays a major role in the control of reproductive hormones in both men and women. Specifically, kisspeptin regulates the release of 'gonadotrophin releasing hormone' (GnRH) from the hypothalamus.

 

What are the benefits of kisspeptin?
Kisspeptin administration improved sexual brain processing in both women and men, resulting in positive effects on sexual behaviour compared to placebo. These are the first clinical studies to explore the ability of kisspeptin to boost sexual pathways in women and men distressed by their low sexual desire.

 

Kisspeptin was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty from the anterior pituitary.
This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH  and LH  in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4's role in programming
tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1.