Oxiracetam’s potential as a memory booster is one of its best known and most studied properties.

Both animal studies‍ and clinical trials on adults with age-related cognitive decline‍ indicate that oxiracetam can improve memory in general, enhancing both memory formation and retention and exerting a significantly positive effect on the speed of recall.‍

There are no studies on how oxiracetam affects users with normal cognitive ability, but anecdotal evidence indicates that it acts as a powerful memory-boosting nootropic, particularly useful to students taking exams‍ or studying logic-intensive subjects such as math.‍

Animal studies on healthy rodents appear to support these reports.‍

Learning Enhancement

Both animal studies and research involving dementia patients indicates that oxiracetam can improve learning ability. This effect may be due to oxiracetam’s ability to improve memory formation and recall speed.

Concentration and Focus

Anecdotally, oxiracetam is reported to improve overall concentration and focus, making it easier to learn for extended periods of time without waning interest or attentiveness.‍

Oxiracetam’s cognitive enhancement effects, combined with its mild stimulant properties, make it attractive to individuals looking for a combination of focus and energy.

Enhanced Verbal Fluency

In studies on elderly subjects with primary or multi-infarct dementia, oxiracetam supplementation was shown to stem symptoms of cognitive decline with a particularly marked positive effect on verbal fluency and verbal learning.

Neuroprotectant

Research suggests that oxiracetam may have a significant neuroprotective effect that could potentially block the brain damage associated with Alzheimer’s disease and other forms of dementia.

In animal studies, brain trauma typical of neurological disorders was modeled by introducing neurotoxins known to impair memory formation. The studies indicated that animals given pre-treatment with oxiracetam were resistant to neurotoxicity.‍

In further testing, oxiracetam was also found to alleviate blood-brain barrier dysfunction and protect against ischemic stroke in rats.

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Mild Stimulant and Promotes Wakefulness

Oxiracetam is a cholinergic, a substance which releases or responds to the neurotransmitter acetylcholine, and as such acts, as a mild psychostimulant.

In animal testing, it was shown to promote arousal and inhibit sleep.‍

Studies also indicate that it may promote wakeful alertness by enhancing blood flow to and within the brain, improving energy metabolism.‍

Oxiracetam is generally well tolerated, and no serious side effects have been reported, even when taken at high dosages.‍

The most commonly reported unpleasant side effect of oxiracetam is headache, which is true of all racetam class nootropics. Racetam related headaches are usually associated with either high dosage or choline depletion, so adding a good choline source to your regimen or reducing the amount of oxiracetam ingested can often eliminate the problem.‍

Because it does have mild stimulant properties, oxiracetam could potentially interfere with normal sleep cycles if taken too late in the day.

Side effects of insomnia and nervousness, while rare, have occasionally been reported.‍These effects can generally be avoided by taking oxiracetam earlier in the day or reducing the dosage.