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How to choose EDTA potassium and potassium?
Release time: 2023-01-10
How to choose EDTA potassium and potassium?
Both potassium EDTA and potassium EDTA are commonly used anticoagulants in vacuum blood collection. The molecular formula of potassium EDTA is C10H18K2N2O10, and the molecular formula of potassium EDTA is C10H13K3N2O8. Although both potassium EDTA and potassium EDTA are white crystal powder in appearance, due to differences in molecular structure, there are huge differences in anticoagulant effect and other uses between potassium EDTA and potassium EDTA.
Through experimental observation, it can be found that the powder of EDTA tri-potassium is more delicate and has better water solubility. In 5% aqueous solution, the PH value of potassium EDTA is about 4.8, which is an acidic liquid; However, the PH value of EDTA tri-potassium is about 7.3, which is closer to the neutral value. Therefore, EDTA tri-potassium has less influence on the PH value of blood samples. In addition, due to the different molecular structures of potassium II and potassium III, potassium III has stronger ability to chelate calcium ions and better anticoagulant effect.
When potassium EDTA and potassium EDTA were added to the plastic blood collection tube, they both appeared dry spray, and the anticoagulant effect of potassium EDTA was higher than that of potassium EDTA; However, when EDTA tri-potassium is added to the glass material vacuum blood collection vessel, EDTA tri-potassium presents a liquid state, which will dilute the blood samples to be tested, thus affecting the count of red blood cells, white blood cells and platelets in the blood, making the detection value lower than the value detected when EDTA di-potassium is used as an anticoagulant.
In other aspects, compared with potassium EDTA, potassium EDTA has more extensive uses. In addition to being used as blood anticoagulant, EDTA is also widely used in daily life, such as adding in washing powder, shampoo, laundry detergent, and can also prepare agricultural chemical spray, toilet deodorant, etc. However, the use of EDTA tri-potassium is relatively simple. At present, it is mostly used as anticoagulant in vacuum blood collection.
It can be seen that EDTA potassium II and potassium III have their respective advantages. Desheng Company specializes in the production of EDTA potassium II and potassium III, and can choose the most suitable products according to their own needs. In addition to EDTA two potassium and three potassium, Desheng also specializes in the production of other blood collection additives, such as serum separation gel, heparin sodium, heparin lithium, and so on. If you want to know more details, please click the official website!