Specification:

Product name: Chelerythrine

CAS: 34316-15-9

Molecular formula: C21H18ClNO4

Molecular structure:

Specifications: Chelerythrin 98%,99% by HPLC

Appearance: white powder

Solubility: Soluble in methanol, ethanol.

Plant source: Toddalia asiatica (L.)Lam.

Grade: Pharmaceutical and food

Description:

Sanguinarine is a quaternary ammonium salt from the group of benzylisoquinoline alkaloids. It is extracted from some plants, including bloodroot (Sanguinaria canadensis), Mexican prickly poppy Argemone mexicana,Chelidonium majus and Macleaya cordata. It is also found in the root, stem and leaves of the opium poppy but not in the capsule.

Sanguinarine is a toxin that kills animal cells through its action on the Na+-K+-ATPase transmembrane protein.Epidemic dropsy is a disease that results from ingesting sanguinarine.

If applied to the skin, sanguinarine kills cells and may destroy tissue. In turn, the bleeding wound may produce a massive scab, called an eschar. For this reason, sanguinarine is termed an escharotic

Numerous published, pre-clinical In Vitro and In Vivo studies have demonstrated that Sanguinarine causes targeted apoptosis in human cancer cells, and recommend future development of Sanguinarine as a potential cancer treatment.A study conducted by the Case Western Reserve University in 2000 found that low doses of sanguinarine caused this apoptosis in cancerous human epidermoid carcinoma cells while little reaction from normal human skin cells was observed.

In plants, sanguinarine is synthesized from dihydrosanguinarine through the action of Dihydrobenzophenanthridine oxidase (EC 1.5.3.12)

Function:

Chelerythrine also can be used for anti-inflammatory

Chelerythrine has effect on anti-carcinoma of esophagus

Chelerythrine haSs the function of spasmolysis for smooth muscle

The functione of resolving phlegm to relieve cough is an important effect of chelerythrin.

Chelerythrine can cause paralysis, cardiac inhibition, and even lead to death on the nerves, heart.

Chelerythrine is used as a functional analgesic action ,the analgesic action can continue 4~48 hours.

The antiviral function of chelerythrine, inhibition gram positive bacteria(GPB) and candida albicans.

Company Introduction
Address: Room 202, Building B8, Huanchuang Enterprise Square, Lugu Street, Yuelu District, Changsha City, Hunan Province
Website: http://www.staherb.cn/
Business scope: Biotechnology, research and development of plant extracts (can be used in the field of pharmaceutical and health products, cosmetics, feed additives and biological pesticide production and development)
Main products: Eucommia extract - chlorogenic acid (5%-98%), ursolic acid (25%-98%), corosolic acid (1%-98%), bitter amygdalin (50%-98%), epimedoside (10%-98%) and other standardized high-purity plant extracts.

If you wanna know more about us, please feel free to contact me at:
Whatsapp: +86 18975842720    sales12 at staherb dot cn
or you can send me online message if it's convenient for you.
We look forward to cooperating with you!