Methyl salicylate is an external analgesic available in over-the-counter (OTC) medicines that temporarily relieve minor body aches and muscle and joint pain associated with backache, arthritis, strains, sprains, and bruises. Methyl salicylate can be found in topical pain medicines (e.g., creams or ointments) that contain more than one external analgesic active ingredient.

Safety guide for methyl salicylate

Methyl salicylate is approved by the U.S. Food and Drug Administration (FDA) and is safe and effective when used according to the Drug Facts label. You should not use more of the medicine or for longer than the label says.

Safe use tips:

You should only apply the medicine to your skin.

You should not tightly bandage the treated area. A tight bandage can trap too much of the active ingredient against your skin.

You should not use a heating pad on the treated area.

Side Effects

Redness, warmth, stinging, or burning on the application site may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Stop using this medication and tell your doctor right away if any of these unlikely but serious side effects occur: blistering/swelling/severe redness at the application site, increased/unusual pain at the application site, nausea/vomiting, ringing in the ears.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.