Physicochemical properties of 3-Iodophenol and its derivatives
Apr 8,2024
3-Iodophenol is a halogenated phenolic compound used as a reagent in esterification, electrophilic aromatic substitution, alkylation, nucleophilic aromatic substitution, Mitsunobu, transition metal-catalysed cross-coupling, acylation and oxidation reactions. Physical Data:?3-fluorophenol, bp = 178?°C, mp = 8–12?°C; 3-chlorophenol, bp = 214?°C, mp = 31–34?°C; 3-bromophenol, bp = 236?°C, mp = 28–32?°C; 3-iodophenol, bp = 190?°C, mp = 42–44?°C. Solubility:?3-fluorophenol and 3-bromophenol are insoluble in H2O; 3-iodophenol is slightly soluble in H2O; 3-chlorophenol is H2O soluble. All reagents are soluble in DMSO. Form Supplied in:?light yellow liquid (3-fluorophenol); light yellow semisolid/liquid (3-chlorophenol, 3-bromophenol); yellow to gray solid (3-iodophenol). Handling, Storage, and Precautions:?all reagents are stable under room temperature and normal pressures. Incompatible with strong oxidizing agents and acid halides.
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