Both substances are considered safe for household use, but it is important to avoid inhaling or ingesting the mixture. It is also recommended to wear gloves and protective eyewear when handling borax and vinegar together.

Undiluted vinegar and borax can also be used for mildew removal. When mixing Borax with other ingredients, it is essential to use warm water to help it dissolve. When borax and vinegar are mixed, a chemical reaction occurs resulting in the formation of a salt, water, and carbon dioxide gas. The carbon dioxide gas is what causes the bubbling or fizzing sensation that is often observed when these two substances are combined.