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Benzyldodecyldimethylammonium Bromide: Applications and Toxicity

Dec 25,2024

General Description

The demand for disinfectants in daily life has dramatically increased as a result of the emergence of SARS-CoV-2. As a typical disinfectant, benzyldodecyldimethylammonium bromide (BDAB) is widely used due to its high efficiency for viral and bacterial inactivation. However, the excessive use of BDAB may significantly increase the release of BDAB in soil, river water, wastewater, and the marine environment. BDAB is structurally stable and has high toxicity to aquatic and soil organisms. Hence, removing excessive BDAB residual from the environment is necessary. Biological methods are the main way to remove BDAB due to the advantage of being environment-friendly, and isolation and screening of BDAB degrading bacteria from the environment become critical. In most instances, microorganisms grow in a co-metabolic manner in the real water treatment environment, and co-metabolic degrading bacteria are more widely present in the environment. Besides, co-metabolic degrading bacteria can use more readily available carbon sources to achieve greater biomass and degradation rates. Therefore, it is more important and practical to screen benzyldodecyldimethylammonium bromide co-metabolic degrading bacteria from the environment.

Figure 1. Benzyldodecyldimethylammonium bromide.png

Figure 1. Benzyldodecyldimethylammonium bromide

Applications

Applications in Disinfection

Benzyldodecyldimethylammonium bromide is primarily recognized for its robust applications as a disinfectant. This compound is classified as a complete disinfectant, meaning it possesses the ability to destroy both spores and vegetative forms of harmful microorganisms. Its high efficacy makes Benzyldodecyldimethylammonium bromide particularly valuable in environments requiring strict sanitation, such as hospitals and laboratories. The compound not only eliminates bacteria and viruses but also maintains stability and does not corrode metal surfaces. This property allows it to be used safely on various equipment without causing damage, making Benzyldodecyldimethylammonium bromide an essential component in infection control protocols.

Applications in Anti-Infective Treatments

The chemical similarity between molybdenum and tungsten makes the direct spectrophotometric determination of these metals impossible. Usually the determination is preceded by a separation step. In order to find out a selective and quantitative isolation method, coprecipitation with thioacetamide and Cu(II) as a carrier; MnO2; cupferron, tannin and crystal violet; quinolin-8-ol, tannin and thioacetamide, were examined. Molybdenum(VI) could be determined in the presence of 100-fold mass excess of tungsten after precipitation with thioacetamide and Cu(II). The remaining methods could only be applied if mass excess of W is equal to or lower with respect to Mo. For the resolution of this problem, the derivative spectrophotometry was used. The studies of different order spectra of gallein complexes of molybdenum, tungsten and their mixtures have shown that the fifth-derivative spectra allows one to eliminate the interfering effects of W on the determination of Mo. At 650 nm the spectral features of tungsten is zeroing while the value of the fifth-derivative spectrum of mixture of Mo and W corresponds only to the concentration of molybdenum in the examined solution. Beer's law is obeyed in the range 0.32–0.80 μg/mL of Mo. The developed derivative spectrophotometric method and the most selective pre-separation method, based on the precipitation of molybdenum(VI) sulphide, were applied to the determination of Mo in Armco iron and steel. The accuracy of the elaborated methods was confirmed by comparison of the determined content of Mo with certified values as well as with the result obtained by the reference ICP? OES technique.1

Toxicity

Toxicity Profile

Benzyldodecyldimethylammonium bromide is classified as a highly toxic substance, with significant acute toxicity risks. The oral lethal dose for rats is reported to be 250 milligrams per kilogram, while the intraperitoneal lethal dose is 90 milligrams per kilogram. These figures indicate that Benzyldodecyldimethylammonium bromide poses a substantial risk to organisms upon exposure, making it critical to handle this compound with caution. Its flammable nature adds another layer of risk, as combustion can produce toxic byproducts such as nitrogen oxides, ammonia, and bromide fumes, thus necessitating safe storage and handling protocols to mitigate hazards. 2

Safety Precautions and Handling Guidelines

When working with Benzyldodecyldimethylammonium bromide, specific safety measures must be observed to ensure the well-being of personnel and the environment. It should never be mixed with ordinary soap, as this can lead to decreased effectiveness and potential hazardous reactions. Additionally, when disinfecting instruments, it is advised to add 0.5 percent sodium nitrite to the preparation. Care should be taken as Benzyldodecyldimethylammonium bromide is unsuitable for disinfecting bladder scopes, ophthalmic instruments, and rubber or aluminum products due to potential material degradation. Therefore, thorough understanding and adherence to safety guidelines are essential when utilizing Benzyldodecyldimethylammonium bromide to prevent harmful exposure and ensure safe application. 2

References:

[1] K. PYTLAKOWSKA  B. F. Spectrophotometric determination of molybdenum in the presence of tungsten using gallein and benzyldodecyldimethylammonium bromide[J]. Journal of Analytical Chemistry, 2012, 68 1. DOI:10.1134/S1061934813010115.

[2] Disinfectants.[J]. Hall’s journal of health, 1874, 21 8.

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Benzyldodecyldimethylammonium bromide manufacturers

  • Benzalkonium Bromide
  • 7281-04-1 Benzalkonium Bromide
  • $10.00 / 1kg
  • 2025-01-03
  • CAS:7281-04-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20 ton