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Recombinant Human  PD-L1/B7-H1/CD274(Fc fusion),Recombinant Human  PD-L1/B7-H1/CD274(Fc fusion)
  • Recombinant Human  PD-L1/B7-H1/CD274(Fc fusion),Recombinant Human  PD-L1/B7-H1/CD274(Fc fusion)

Recombinant Human PD-L1/B7-H1/CD274(Fc fusion)

價格 12540.00 17920.00 720.00 1680.00
包裝 500ug 1mg 10ug 50ug
最小起訂量 10ug
發(fā)貨地 北京
更新日期 2024-10-31
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產品詳情

中文名稱:Recombinant Human PD-L1/B7-H1/CD274(Fc fusion)英文名稱:Recombinant Human PD-L1/B7-H1/CD274(Fc fusion)
Derived from: Human cellsEndotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.Purity: Greater than 95% as determined by reducing SDS-PAGE.
產品編號: P00219品牌: Solarbio
2024-10-31 Recombinant Human PD-L1/B7-H1/CD274(Fc fusion) Recombinant Human PD-L1/B7-H1/CD274(Fc fusion) 500ug/12540.00RMB;1mg/17920.00RMB;10ug/720.00RMB;50ug/1680.00RMB 12540.00

Recombinant Human Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr239 is expressed with a Fc tag at the C-terminus.

Storage

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months

Background

CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.

Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Known as

Programmed Cell Death 1 Ligand 1; PD-L1; PDCD1 Ligand 1; Programmed Death Ligand 1; B7 Homolog 1; B7-H1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
關鍵字: Recombinant Human PD-L1/B7-H1/CD274(Fc fusion);細胞生物學

公司簡介

北京索萊寶科技有限公司是一家集研發(fā)、生產、銷售、服務于一體的高科技生物企業(yè)。技術推廣;技術轉讓;技術咨詢;技術服務;生物試劑技術開發(fā);銷售生物試劑盒、實驗室專用化學試劑、實驗室專用設備、辦公用品、化工產品(不含危險化學品)、計算機軟件及輔助設備;貨物進出口、技術進出口、代理進出口;委托加工生產生物制品、生化制品、化工產品(不含危險化學品);生產生物試劑盒;批發(fā)第一類醫(yī)療器械、第二類醫(yī)療器械;批發(fā)第三類醫(yī)療器械。
成立日期 2004-09-22 (21年) 注冊資本 1000萬元
員工人數 50-100人 年營業(yè)額 ¥ 500萬-1000萬
主營行業(yè) 分析化學,生物化工,化學試劑,醫(yī)藥原料,儀器耗材 經營模式 貿易,工廠,試劑
  • 北京索萊寶科技有限公司
VIP 9年
  • 公司成立:21年
  • 注冊資本:1000萬元
  • 企業(yè)類型:有限責任公司
  • 主營產品:tris,甘氨酸,瓊脂粉,潮霉素B,SDS,BSA
  • 公司地址:聯東U谷景盛南四街85A三層
詢盤

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