價格 | 詢價 |
包裝 | 20μg |
最小起訂量 | 20μg |
發(fā)貨地 | 上海 |
更新日期 | 2025-01-30 |
中文名稱:Recombinant Equine IL-1RA | 英文名稱:Recombinant Equine IL-1RA |
有效期: 一年 | 產品類別: 重組蛋白 細胞因子 |
產品編號 | 產品名稱 | 產品包裝 | 產品價格 |
P6474-20μg | Recombinant Equine IL-1RA | 20μg | 1159.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Equine | 100034236 | O18999 | E. coli | 152aa | 17.4kDa | - |
About this Antibody | |
Name | Recombinant Equine IL-1RA (Recombinant Equine Interleukin-1 Receptor Antagonist; rEqIL-1RA);重組馬白細胞介素1受體拮抗劑 |
Synonyms | IL-1F3; IL1RN; DIRA; ICIL-1RA; IL1F3; IL1RA; IL-1ra; IL-1ra3; IL1RN; IL-1RN; interleukin 1 receptor antagonist; IRAP; MVCD4 |
Purity | >95% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 3.0μg/ml, corresponding to a specific activity of >333IU/mg in the presence of 50pg/ml rHuIL-1α. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4. |
Endotoxin | Less than 1EU/μg of rEqIL-1RA as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Cytokine |
Background | IL-1RA was initially called the IL-1 inhibitor which is encoded by the IL1RN gene and it is a member of the interleukin 1 cytokine family. It is secreted by various types of cells including immune cells, epithelial cells, and adipocytes. IL-1RA has functions of inhibiting the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. IL-1RA is also used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role. The equus caballus IL-1RA is a single non-glycosylated polypeptide chain containing 152 amino acids and it has been shown to block the inflammatory responses induced by IL-1 both in vitro and in vivo. The protein shows 26% amino acid homology to IL-1β and 19% homology to IL-1α. It also shares 78%~80%a.a. sequence identity with murine, rat, porcine IL-1RA. |
Amino Acid Sequence | HPLGKRPCKM QAFRIWDVNQ KTFYMRNNQL VAGYLQESNT KLQEKIDVVP IEPDALFLGL HGRKLCLACV KSGDEIRFQL EAVNITDLSK NKEENKRFTF IRSNSGPTTS FESAACPGWF LCTAQEADRP VSLTNKPKES FMVTKFYLQE DQ |
包裝清單:
產品編號 | 產品名稱 | 包裝 |
P6474-5μg | Recombinant Equine IL-1RA | 5μg |
P6474-20μg | Recombinant Equine IL-1RA | 20μg |
P6474-100μg | Recombinant Equine IL-1RA | 100μg |
P6474-1mg | Recombinant Equine IL-1RA | 1mg |
- | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會引起部分失活,所以首次配制成相應濃度的儲存液后(請根據產品簡介中Reconstitution一欄的信息配制儲存液),須分裝后-20℃或更低溫度凍存,以避免反復凍融。
注意事項:
???????由于有些塑料管壁對某些蛋白有較強的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結合位點,使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產品簡介中Reconstitution一欄的信息配制儲存液。
???????本產品僅限于專業(yè)人員的科學研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內。
???????為了您的安全和健康,請穿實驗服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊資本 | 1000.000000萬人民幣 |
員工人數 | 500人以上 | 年營業(yè)額 | ¥ 500萬-1000萬 |
主營行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學,生物活性小分子 | 經營模式 | 試劑 |
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