價格 | 詢價 |
包裝 | 100μg |
最小起訂量 | 100μg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-25 |
中文名稱:Recombinant Human IL-13, Variant | 英文名稱:Recombinant Human IL-13, Variant |
有效期: 一年 | 產(chǎn)品類別: 重組蛋白 細胞因子 |
產(chǎn)品編號 | 產(chǎn)品名稱 | 產(chǎn)品包裝 | 產(chǎn)品價格 |
P5183-100μg | Recombinant Human IL-13, Variant | 100μg | 4759.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Human | 3596 | P35225 | E. coli | 112aa | 12.3kDa | - |
About this protein | |
Name | Recombinant Human IL-13, Variant (Recombinant Human Interleukin-13, Variant; rHuIL-13, Variant);重組人白細胞介素13變體 |
Synonyms | IL-13; P600 |
Purity | >97% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×106IU/mg. |
Physical Appearance | Sterile Filtered lyophilized (freeze-dried) liquid-like powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.2, with 5% trehalose. |
Endotoxin | Less than 1EU/μg of rHuIL-13, Variant as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Cytokine |
Background |
Human Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 5. IL-13 is a 132 amino acid protein containing a proposed 20 amino acid signal peptide, and shares approximately 30% amino acid sequence homology to human IL-4. Additionally, the two cytokines exhibit overlapping biological activities. Human IL-13 is produced by activated Th0, Th1-like Th2-like and CD8 T cells. Similarly to IL-4, IL-13 has multiple effects on the differentiation and functions of monocytes/macrophages. IL-13 can suppress the cytotoxic functions of monocytes/macrophages. IL-13 variant is a natural variant of IL-13 and has a Q instead of R112 of wild type, which associated with increased risk for asthma development and at homozygosity associated with higher levels of serum total IgE in some allergic rhinitis patients. |
Amino Acid Sequence | GPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGQ FN |
包裝清單:
產(chǎn)品編號 | 產(chǎn)品名稱 | 包裝 |
P5183-2μg | Recombinant Human IL-13, Variant | 2μg |
P5183-10μg | Recombinant Human IL-13, Variant | 10μg |
P5183-100μg | Recombinant Human IL-13, Variant | 100μg |
P5183-1mg | Recombinant Human IL-13, Variant | 1mg |
- | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會引起部分失活,所以首次配制成相應(yīng)濃度的儲存液后(請根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項:
???????由于有些塑料管壁對某些蛋白有較強的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點,使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
???????本產(chǎn)品在凍干時添加了海藻糖作為保護劑,此時凍干后本產(chǎn)品看起來仍然像是液體,屬于正?,F(xiàn)象。在凍干工藝上,海藻糖作為常用的凍干保護劑,可顯著阻止蛋白質(zhì)二級結(jié)構(gòu)的改變,防止凍干過程中的蛋白變性。
???????本產(chǎn)品僅限于專業(yè)人員的科學研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請穿實驗服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊資本 | 1000.000000萬人民幣 |
員工人數(shù) | 500人以上 | 年營業(yè)額 | ¥ 500萬-1000萬 |
主營行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學,生物活性小分子 | 經(jīng)營模式 | 試劑 |
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