價(jià)格 | 詢(xún)價(jià) |
包裝 | 10μg |
最小起訂量 | 10μg |
發(fā)貨地 | 上海 |
更新日期 | 2025-01-30 |
中文名稱(chēng):Recombinant Human PAI-2 | 英文名稱(chēng):Recombinant Human PAI-2 |
有效期: 一年 | 產(chǎn)品類(lèi)別: 重組蛋白 其他重組蛋白 |
產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | 產(chǎn)品包裝 | 產(chǎn)品價(jià)格 |
P7037-10μg | Recombinant Human PAI-2 | 10μg | 1152.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Human | 5055 | P05120 | E. coli | 415aa | 46.6kDa | - |
About this Antibody | |
Name | Recombinant Human PAI-2 (Recombinant Human Plasminogen Activator Inhibitor-2; rHuPAI-2);重組人纖溶酶原激活物抑制因子 |
Synonyms | PAI2; PLANH2; Urokinase Inhibitor; HsT1201; Monocyte Arg-serpin; PAI; PAI2Urokinase inhibitor; Placental plasminogen activator inhibitor; PLANH2PAI-2; plasminogen activator inhibitor 2; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; Serpin B2; serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
Purity | >95% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37℃. Half maximal inhibition against 1.0μg/ml of single chain tPA was at a concentration of 1.0μg/ml. |
Physical Appearance | Sterile Filtered lyophilized (freeze-dried) liquid-like powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH8.0, 150mM NaCl, 1mM Cysteine, with 5% Trehalose. |
Endotoxin | Less than 0.1EU/μg of rHuPAI-2 as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Enzymes |
Background | PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47kDa non-glycosylated intracellular protein which can be induced to be secreted as 60kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. |
Amino Acid Sequence | MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVTP MTPENFTSCG FMQQIQKGSY PDAILQAQAA DKIHSSFRSL SSAINASTGN YLLESVNKLF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV DGDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFRVNSAQRT PVQMMYLREK LNIGYIEDLK AQILELPYAG DVSMFLLLPD EIADVSTGLE LLESEITYDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYEL RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TGHGGPQFVA DHPFLFLIMH KITNCILFFG RFSSP |
包裝清單:
產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | 包裝 |
P7037-2μg | Recombinant Human PAI-2 | 2μg |
P7037-10μg | Recombinant Human PAI-2 | 10μg |
P7037-100μg | Recombinant Human PAI-2 | 100μg |
P7037-1mg | Recombinant Human PAI-2 | 1mg |
- | 說(shuō)明書(shū) | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活,所以首次配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項(xiàng):
???????由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
???????本產(chǎn)品在凍干時(shí)添加了海藻糖作為保護(hù)劑,此時(shí)凍干后本產(chǎn)品看起來(lái)仍然像是液體,屬于正常現(xiàn)象。在凍干工藝上,海藻糖作為常用的凍干保護(hù)劑,可顯著阻止蛋白質(zhì)二級(jí)結(jié)構(gòu)的改變,防止凍干過(guò)程中的蛋白變性。
???????本產(chǎn)品僅限于專(zhuān)業(yè)人員的科學(xué)研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊(cè)資本 | 1000.000000萬(wàn)人民幣 |
員工人數(shù) | 500人以上 | 年?duì)I業(yè)額 | ¥ 500萬(wàn)-1000萬(wàn) |
主營(yíng)行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學(xué),生物活性小分子 | 經(jīng)營(yíng)模式 | 試劑 |
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