價(jià)格 | 詢價(jià) |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-11-05 |
中文名稱:Recombinant Human UBE2R1 | 英文名稱:Recombinant Human UBE2R1 |
有效期: 一年 | 產(chǎn)品類別: 重組蛋白 其他重組蛋白 |
產(chǎn)品編號(hào) | 產(chǎn)品名稱 | 產(chǎn)品包裝 | 產(chǎn)品價(jià)格 |
P7136-1mg | Recombinant Human UBE2R1 | 1mg | 12354.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Human | 997 | P49427 | E. coli | 236aa | 26.7kDa | - |
About this Antibody | |
Name | Recombinant Human UBE2R1 (Recombinant Human Ubiquitin Conjugating Enzyme E2 R1; rHuUBE2R1);重組人泛素結(jié)合酶E2R1 |
Synonyms | Cdc34; UBC3; UBE2R1; cell division cycle 34; cell division cycle 34 homolog (S. cerevisiae); E2-CDC34; EC 6.3.2.19; UBC3; UBE2R1UBCH3; ubiquitin carrier protein; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; Ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1 |
Purity | >95% by SDS-PAGE and HPLC analyses. |
Biological Activity | Data is not available. |
Physical Appearance | Sterile Filtered lyophilized (freeze-dried) liquid-like powder. |
Formulation | A 0.2μm filtered concentrated solution in 50mM HEPES, pH7.0, with 125mM NaCl, 10% Glycerol, 5% Trehalose, 1mM DTT. |
Endotoxin | Less than 0.1EU/μg of rHuUBE2R1 as determined by LAL method. |
Reconstitution | N/A |
Category | Ubiquitins |
Background | Ubiquitin-conjugating enzyme E2 R1 belongs to the ubiquitin-conjugating enzyme family and is encoded by the UBE2R1 gene in humans. The ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, take part in the second step in the ubiquitination reaction. In this reaction, E1 activates the ubiquitin by covalently attaching the molecule to its active site cysteine residue. The activated ubiquitin is then transferred to an E2 cysteine and then the E2 molecule binds E3 via a structurally conserved binding region. UBE2R1 is important in the control of cell cycle and DNA replication. In vitro it catalyzes 'Lys-48'-linked polyubiquitination. Additionally, the protein cooperates with the UBCH5C and the SCF ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. |
Amino Acid Sequence | MARPLVPSSQ KALLLELKGL QEEPVEGFRV TLVDEGDLYN WEVAIFGPPN TYYEGGYFKA RLKFPIDYPY SPPAFRFLTK MWHPNIYETG DVCISILHPP VDDPQSGELP SERWNPTQNV RTILLSVISL LNEPNTFSPA NVDASVMYRK WKESKGKDRE YTDIIRKQVL GTKVDAERDG VKVPTTLAEY CVKTKAPAPD EGSDLFYDDY YEDGEVEEEA DSCFGDDEDD SGTEES |
包裝清單:
產(chǎn)品編號(hào) | 產(chǎn)品名稱 | 包裝 |
P7136-5μg | Recombinant Human UBE2R1 | 5μg |
P7136-20μg | Recombinant Human UBE2R1 | 20μg |
P7136-100μg | Recombinant Human UBE2R1 | 100μg |
P7136-1mg | Recombinant Human UBE2R1 | 1mg |
- | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活,所以首次配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項(xiàng):
???????由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
???????本產(chǎn)品在凍干時(shí)添加了海藻糖作為保護(hù)劑,此時(shí)凍干后本產(chǎn)品看起來仍然像是液體,屬于正?,F(xiàn)象。在凍干工藝上,海藻糖作為常用的凍干保護(hù)劑,可顯著阻止蛋白質(zhì)二級(jí)結(jié)構(gòu)的改變,防止凍干過程中的蛋白變性。
???????本產(chǎn)品僅限于專業(yè)人員的科學(xué)研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊(cè)資本 | 1000.000000萬人民幣 |
員工人數(shù) | 500人以上 | 年?duì)I業(yè)額 | ¥ 500萬-1000萬 |
主營(yíng)行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學(xué),生物活性小分子 | 經(jīng)營(yíng)模式 | 試劑 |
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