價格 | 詢價 |
包裝 | 2μg |
最小起訂量 | 2μg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-25 |
中文名稱:Recombinant Murine Bcl-xL | 英文名稱:Recombinant Murine Bcl-xL |
有效期: 一年 | 產(chǎn)品類別: 重組蛋白 其他重組蛋白 |
產(chǎn)品編號 | 產(chǎn)品名稱 | 產(chǎn)品包裝 | 產(chǎn)品價格 |
P7343-2μg | Recombinant Murine Bcl-xL | 2μg | 464.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Mouse | 12048 | Q64373 | E. coli | 211aa | 23.7kDa | - |
About this Antibody | |
Name | Recombinant Murine Bcl-xL (Recombinant Murine B-cell Lymphoma-extra Large; rMuc);Recombinant Mouse Bcl-xL ;?重組小鼠B細胞淋巴瘤xL |
Synonyms | Apoptosis regulator Bcl-X; bcl2-L-1; Bcl2-L-1; BCL2-like 1; bcl-2-like protein 1; BCLXBCL2LBcl-X; BCLXL; bcl-xL; BCL-XL/S; BCLXS; bcl-xS; DKFZp781P2092 |
Purity | >97% by SDS-PAGE and HPLC analyses. |
Biological Activity | Test in Process. |
Physical Appearance | Sterile Filtered lyophilized (freeze-dried) liquid-like powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4, 5% Trehalose. |
Endotoxin | Less than 0.1EU/μg of rMuBcl-xL as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Others |
Background | Bcl-X, also named as BCL2L1 or BCL2L, belongs to the Bcl-2 family and is encoded by the BCL2L1 gene in human. Alternative splicing of Bcl-X results in at least two isoforms,isoform Bcl-X(L) (also named as Bcl-xL) and isoform Bcl-x(S) (also named as Bcl-xS). Bcl-xL is found in tissues containing long-lived postmitotic cells, such as adult brain, while Bcl-xS is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Bcl-X forms homodimer or heterodimer with other Bcl-2 proteins, like BAK, BAX or Bcl-2, to act as anti- or pro- apoptotic regulators. Bcl-xL appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane, and it also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. In contrast, Bcl-xS is a pro-apoptotic protein that promotes apoptosis. |
Amino Acid Sequence |
SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R |
包裝清單:
產(chǎn)品編號 | 產(chǎn)品名稱 | 包裝 |
P7343-2μg | Recombinant Murine Bcl-xL | 2μg |
P7343-10μg | Recombinant Murine Bcl-xL | 10μg |
P7343-100μg | Recombinant Murine Bcl-xL | 100μg |
P7343-1mg | Recombinant Murine Bcl-xL | 1mg |
- | 說明書 | 1份 |
保存條件:
???????-20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會引起部分失活,所以首次配制成相應濃度的儲存液后(請根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液),須分裝后-20℃或更低溫度凍存,以避免反復凍融。
注意事項:
???????由于有些塑料管壁對某些蛋白有較強的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結(jié)合位點,使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
???????本產(chǎn)品在凍干時添加了海藻糖作為保護劑,此時凍干后本產(chǎn)品看起來仍然像是液體,屬于正?,F(xiàn)象。在凍干工藝上,海藻糖作為常用的凍干保護劑,可顯著阻止蛋白質(zhì)二級結(jié)構(gòu)的改變,防止凍干過程中的蛋白變性。
???????本產(chǎn)品僅限于專業(yè)人員的科學研究用,不得用于臨床診斷或治療,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
???????為了您的安全和健康,請穿實驗服并戴一次性手套操作。
成立日期 | 2007-07-19 (18年) | 注冊資本 | 1000.000000萬人民幣 |
員工人數(shù) | 500人以上 | 年營業(yè)額 | ¥ 500萬-1000萬 |
主營行業(yè) | 生化試劑,核苷,核苷酸,寡核苷酸,抗體,蛋白組學,生物活性小分子 | 經(jīng)營模式 | 試劑 |
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