Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

15200

Q06186

E. coli

86aa

9.8kDa

－

About this Antibody

Name

Recombinant Murine HB-EGF (Recombinant Murine Heparin-binding EGF-like Growth Factor; rMuHB-EGF)；Recombinant Mouse HB-EGF ;?重組小鼠肝素結(jié)合表皮生長因子樣生長因子

Synonyms

Dtr; Dts; Hegfl; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor); DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor); DTS; DTSF; heparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml, corresponding to a specific activity of >1.0×10⁶IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 10mM PB, 500mM NaCl, pH7.4.

Endotoxin

Less than 1EU/μg of rMuHB-EGF as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Heparin-binding epidermal growth factor (HB-EGF)-like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation and wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. The protein is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. Murine HB-EGF shares about 81%a.a. sequence identity with human HB-EGF.

Amino Acid Sequence

DLEGTDLNLF KVAFSSKPQG LATPSKERNG KKKKKGKGLG KKRDPCLRKY KDYCIHGECR YLQEFRTPSC KCLPGYHGHR CHGLTL

產(chǎn)品編號

產(chǎn)品名稱

包裝

P6128-10μg

Recombinant Murine HB-EGF

10μg

P6128-50μg

Recombinant Murine HB-EGF

50μg

P6128-100μg

Recombinant Murine HB-EGF

100μg

P6128-1mg

Recombinant Murine HB-EGF

1mg

-

說明書

1份