Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

89808

O55145

E. coli

76aa

8.8kDa

－

About this Antibody

Name

Recombinant Rat Fractalkine/CX3CL1 (Recombinant Rat Fractalkine/CX3CL1; rRtFractalkine/CX3CL1)；重組大鼠膜結(jié)合型趨化因子/CX3CL1

Synonyms

FKN; Fractalkine; Neurotactin; ABCD-3; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C membrane-anchored chemokine; CXC3; CXC3C; FKN; fractalkine; Neurotactin; neurotactin; neurotactin); NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine; NTTSmall-inducible cytokine D1; SCYD1C-X3-C motif chemokine 1; small inducible cytokine subfamily D (Cys-X3-Cys), member-1

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-10ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRtFractalkine/CX3CL1 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CX3CL1 recently identified through bioinformatics is the only known member of the CX3C chemokine family and it is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucinlike talk. The soluble form of CX3CL1 is chemotactic for T-cells and monocytes, but not for neutrophils. In addition, it may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Recombinant Rat CX3CL1 contains 76 amino acids and it shares approximately 86% and 83% amino acid sequence homology with the murine and human protein.

Amino Acid Sequence

QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG

產(chǎn)品編號

產(chǎn)品名稱

包裝

P6902-5μg

Recombinant Rat Fractalkine/CX3CL1

5μg

P6902-20μg

Recombinant Rat Fractalkine/CX3CL1

20μg

P6902-100μg

Recombinant Rat Fractalkine/CX3CL1

100μg

P6902-1mg

Recombinant Rat Fractalkine/CX3CL1

1mg

-

說明書

1份