Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

287287

P20096

E. coli

125aa

14kDa

－

About this Antibody

Name

Recombinant Rat IL-4 (Recombinant Rat Interleukin-4; rRtIL-4)；重組大鼠白細(xì)胞介素4

Synonyms

BCDF; BSF1; B cell growth factor 1; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; Binetrakin; BSF1; BSF-1; IL-4B_cell stimulatory factor 1; interleukin 4; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra; pitrakinra

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat splenocytes is less than 1.0ng/ml, corresponding to a specific activity of >1.0×10⁶IU/mg.

Physical Appearance

Sterile Filtered lyophilized (freeze-dried) liquid-like powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, 5% trehalose.

Endotoxin

Less than 1EU/μg of rRtIL-4 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-4 (IL-4) is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by mast cells, activated T cells and bone marrow stromal cells. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4⁺ T-cells into Th2 cells. IL-4 can enhance both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. The rat IL-4 shares about 40% ~ 45%a.a. sequence identity with human, mouse, rhesus macaque IL-4 and they are species-specific in their activities.

Amino Acid Sequence

HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS CTSMS

產(chǎn)品編號

產(chǎn)品名稱

包裝

P6267-5μg

Recombinant Rat IL-4

5μg

P6267-20μg

Recombinant Rat IL-4

20μg

P6267-100μg

Recombinant Rat IL-4

100μg

P6267-1mg

Recombinant Rat IL-4

1mg

-

說明書

1份