Species

Gene ID

Accession

Source

Length

MW

Tag

Rhesus Macaque

708117

F7ANQ9

E. coli

91aa

10.6kDa

－

About this Antibody

Name

Recombinant Rhesus Macaque S100B (Recombinant Rhesus Macaque S100 Calcium Binding Protein B; rRhS100B)；重組恒河猴S100鈣結(jié)合蛋白B

Synonyms

Protein S100; S100 calcium-binding protein; S100B

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Data Not Available.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rRhS100B as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

S100B belongs to the S100 family, which containing 2 EF-hand calcium-binding motifs. In humans, S100B protein is encoded by the S100P gene located at 4q16, but genes that encode other numbers of s100 family proteins are almost located at 1q21 as a cluster. S100B is glial-specific and is expressed primarily by astrocytes. Not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and byng2-expressing cells. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca²⁺ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.

Amino Acid Sequence

SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E

產(chǎn)品編號

產(chǎn)品名稱

包裝

P5889-2μg

Recombinant Rhesus Macaque S100B

2μg

P5889-10μg

Recombinant Rhesus Macaque S100B

10μg

P5889-100μg

Recombinant Rhesus Macaque S100B

100μg

P5889-1mg

Recombinant Rhesus Macaque S100B

1mg

-

說明書

1份