Species

Gene ID

Accession

Source

Length

MW

Tag

Rhesus Macaque

574180

Q8HYP9

E. coli

71aa

8.1kDa

－

About this Antibody

Name

Recombinant Rhesus Macaque TARC/CCL17 (Recombinant Rhesus Macaque Thymus and Activation Regulated Chemokine/CCL17; rRhTARC/CCL17)；重組恒河猴胸腺活化調(diào)節(jié)趨化因子/CCL17

Synonyms

C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine; TARC

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, 300mM NaCl, pH 7.4, with 0.02% Tween-20.

Endotoxin

Less than 0.1EU/μg of rRhTARC/CCL17 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL17 also known as thymus and activation-related chemokine (TARC) is encoded by the CCL17 gene. It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently. CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes. It plays an important role in skin diseases such as atopic dermatitis, bullous pemphigoid and mycosis fungoides. CCL17 has approximately 24-29% amino acid sequence identity with RANTES, MIP-1α, MIP-1β, MCP-1, MCP-2, MCP-3 and I-309.

Amino Acid Sequence

ARGTNVGREC CLKYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQNKAIC SDPNDKKVKK ALKYLQSLER S

產(chǎn)品編號

產(chǎn)品名稱

包裝

P6702-2μg

Recombinant Rhesus Macaque TARC/CCL17

2μg

P6702-10μg

Recombinant Rhesus Macaque TARC/CCL17

10μg

P6702-100μg

Recombinant Rhesus Macaque TARC/CCL17

100μg

P6702-1mg

Recombinant Rhesus Macaque TARC/CCL17

1mg

-

說明書

1份