產(chǎn)品名稱:乙?;邹继J醇
化學(xué) 名:3,4’,5-三乙酰氧基反式二苯乙烯
產(chǎn)品規(guī)格:98%
檢測(cè)方法:HPLC
分子 式:C20H18O6
分子 量:354.35
CAS 號(hào):42206-94-0
產(chǎn)品外觀:白色或類白色粉末
產(chǎn)品描述:乙?;邹继J醇是白藜蘆醇的基礎(chǔ)上進(jìn)行一步化學(xué)合成的的衍生產(chǎn)品。乙酰化白藜蘆醇進(jìn)入體內(nèi)后,在體內(nèi)轉(zhuǎn)變?yōu)榘邹继J醇,發(fā)揮其生物活性,它相對(duì)于白藜蘆醇來(lái)說(shuō)具備以下特點(diǎn):
1.穩(wěn)定性增強(qiáng);
2.生物利用度提高,由于延長(zhǎng)了體內(nèi)的停留時(shí)間,提高了半衰期,生物利用度較好。
產(chǎn)品應(yīng)用:乙?;邹继J醇可廣泛應(yīng)用于食品,飲料及保健品方面。
Production Name:Acetyl-resveratrol
Specification:98%
Test Method:HPLC
Synonyms:Acetyl trans-resveratrol;1,3-Benzenediol,5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-, diacetate (9CI);1,3-Benzenediol,5-[2-[4-(acetyloxy)phenyl]ethenyl]-, diacetate, (E)-;3,4,5-Triacetoxy-trans-stilbene;3,5,4-Tri-O-acetylresveratrol;trans-Resveratrol triacetate
Molecular Formula:C20H18O6
Molecular Weight:354.35
CAS No:42206-94-0
Appearance: White to off-white powder
Description:Acetyl -resveratrol is called prodrug on medicinal chemistry. Hydroxyls are replaced by acetyls.
Acetyl-resveratrol is more stable than trans-resveratrol. When absorbed, it returns to resveratrol under action of metabolism.
The main drawback with current resveratrol forms is the low oral bioavailability. Resveratrol is water-insoluble substance; it can be easily excreted when intaked. This is why finding these acetylated analogs has been so significant; they have better bioavailability and increased biological activity in comparison to the base phenolic compounds. Multiple studies have shown that acetylated analogs of Resveratrol exhibit the same or higher inhibitory effects on various tumor cell lines than Resveratrol itself while being absorbed faster and resisting cellular breakdown. Since the acetylated Resveratrol is being absorbed more quickly, plasma levels in the body reach a higher level and at a faster rate. Through ester hydrolysis enzymes in the body actually break down acetylated Resveratrol back to its natural phenolic form.
Dosage form varied from pill to capsule up to different requirements when use Acetyl-resveratrol as raw material.
Resveratrol is unstable because its Hydroxyls are active group when exposure to oxygen, light and heat. The purpose of acetylation is to inactivate Resveratrol before absorption.
Acetyl-resveratrol is soluble in water (but not resveratrol). Therefore, it can be widely used in cosmetic industry, pharmaceutics, food, beverage, health products.
關(guān)鍵字: 98%乙?;邹继J醇;Acetyl-resveratrol;虎杖
Changsha Huir (CSHR) has been dedicated to the research and development of herbal and nutraceutical ingredients since 1997. for the past 10years , We strictly control the quality from raw material to the finished product, and make our spirits of pursuing perfect embody in our herbal extract products field.