Human NKp44 / NCR2 / CD336 Protein, Llama IgG2b Fc Tag, low endotoxin
分子別名(Synonym)
NKp44,NCR2,CD336,LY95
表達(dá)區(qū)間及表達(dá)系統(tǒng)(Source)
Human NKp44, Llama IgG2b Fc Tag (NC2-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Ala 192 (Accession # O95944-1).
Predicted N-terminus: Gln 22
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a llama IgG2b Fc tag at the C-terminus.
The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 0.01 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
NKp44是天然細(xì)胞毒性受體(NCR)的成員,是一種激活受體,在激活的NK細(xì)胞和其他NKp44+免疫細(xì)胞發(fā)揮的大多數(shù)功能中起著至關(guān)重要的作用。膜相關(guān)PCNA是NKp44(NCR2)先天免疫受體的配體。NKp44/NCR2/CD336可能有助于提高活化的自然殺傷(NK)細(xì)胞介導(dǎo)腫瘤細(xì)胞裂解的效率。
關(guān)鍵字: NKp44;NKp44蛋白;NKp44重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。