Human AMIGO2 Protein, His Tag
分子別名(Synonym)
AMIGO2
表達區(qū)間及表達系統(tǒng)(Source)
Human AMIGO2, His Tag (AM2-H52H5) is expressed from human 293 cells (HEK293). It contains AA Val 31 - Thr 398 (Accession # Q86SJ2-1).
Predicted N-terminus: Val 31
蛋白結構(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 43.5 kDa. The protein migrates as 58-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
癌癥是最常見的惡性腫瘤之一,肝是胃癌血行轉移最常見的部位。AMIGO2是一種I型跨膜蛋白,與腺癌中的腫瘤細胞粘附有關;然而,其在GC中的重要性尚未確定。但更多的數(shù)據(jù)表明,AMIGO2是一種新型抗轉移治療方法的新靶點,旨在阻斷轉移性腫瘤球體的內聚力、存活率和粘附性。
關鍵字: AMIGO2;AMIGO2蛋白;AMIGO2重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。