InVivoMAb anti-mouse NK1.1
BioXCell 小鼠 NK1.1抗體
BE0036
Product Citations:
267
Clone:
PK136
Reactivities:
Mouse
Product Details
The PK136 monoclonal antibody reacts with mouse NK1.1 also known as CD161b/CD161c, KLRB1, NKR-P1A and Ly-55. NK1.1 is
a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by the Klrb1c/NKR-P1C gene. NK1.1
plays roles in NK cell activation and differentiation, IFN-γ production, cytotoxic granule release, and is thought to be involved
in the generation of Th2 cells. NK1.1 is predominantly expressed as a disulfide-linked homodimer on NK cells however, it is also
expressed on NK-T cells, a rare population of T lymphocytes. NK 1.1 is only expressed by C57BL/6, FVB/N, and NZB strains of
mice and not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129 strains.
Isotype Mouse IgG2a, κ
Recommended Isotype Control(s) InVivoMAb mouse IgG2a isotype control, unknown specificity
Recommended Dilution Buffer InVivoPure pH 7.0 Dilution Buffer
Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen Mouse spleen and bone marrow cells enriched for NK1+ cells
Reported Applications in vivo NK cell depletion
Flow cytometry
Formulation PBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin <2EU/mg (<0.002EU/μg)
Determined by LAL gel clotting assay
Purity >95%
Determined by SDS-PAGE
Sterility 0.2 μm filtration
Production Purified from cell culture supernatant in an animal-free facility
Purification Protein A
RRID AB_1107737
Molecular Weight 150 kDa
StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
關(guān)鍵字： BioXCell 小鼠 NK1.1抗體;
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