BST1產(chǎn)品信息
英文名稱：ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
中文名稱：ADP-核糖基化酶/環(huán)腺苷二磷酸核糖水解酶-2
靶點別稱：BST1,CD157
物種：Human
標簽：His Tag
屬性：Protein
標記：Unconjugated
表達區(qū)間及表達系統(tǒng)（Source）
Human BST1, His Tag (BS1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 29 - Ala 293 (Accession # Q10588-1).
Predicted N-terminus: Gly 29
蛋白結(jié)構(gòu)（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 32.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
骨髓基質(zhì)細胞抗原-1（BST-1）或CD157是一種基質(zhì)細胞系衍生的糖基磷脂酰肌醇錨定分子，屬于CD38家族。CD157是在骨髓基質(zhì)細胞系中發(fā)現(xiàn)的，它促進了前B細胞的生長。BST1在類風(fēng)濕性關(guān)節(jié)炎患者骨髓基質(zhì)細胞系中的表達增強。類風(fēng)濕性關(guān)節(jié)炎中的多克隆B細胞異?？赡苤辽俨糠謿w因于基質(zhì)細胞群中BST1的過表達。
關(guān)鍵字： BST1;BST1蛋白;BST1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。