Human IGFBP-6 Protein, His Tag

分子別名（Synonym）

IGFBP6,IBP6

表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）

Human IGFBP-6 Protein, His Tag (IG6-H52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 28 - Gly 240 (Accession # P24592).

Predicted N-terminus: Arg 28

蛋白結(jié)構(gòu)（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 24.5 kDa. The protein migrates as 30-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>90% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

IGFBP6（胰島素樣生長因子結(jié)合蛋白6）是胰島素樣生長因素結(jié)合蛋白（IGFBP）家族的成員。與其他IGFBPs一樣，IGFBP6可以與胰島素樣生長因子（IGFs）結(jié)合，并調(diào)節(jié)其在體內(nèi)的活性和分布。IGFBP6是IGF信號通路的重要調(diào)節(jié)因子。它調(diào)節(jié)IGFs的活性和可用性，影響細(xì)胞過程，并在發(fā)育和疾病中發(fā)揮作用。