LAMP1產(chǎn)品信息

英文名稱(chēng)：Lysosome-associated membrane glycoprotein 1

中文名稱(chēng)：溶酶體相關(guān)膜糖蛋白1

靶點(diǎn)別稱(chēng)：CD107a，LAMP1

物種：Human

標(biāo)簽：His Tag

屬性：Protein

標(biāo)記：Unconjugated

表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）

Human LAMP1, His Tag (LA1-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 29 - Met 382 (Accession # NP_005552).

Predicted N-terminus: Ala 29

蛋白結(jié)構(gòu)（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 39.2 kDa. The protein migrates as 55-95 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

溶酶體相關(guān)膜蛋白1（LAMP1）也被稱(chēng)為CD107a（分化簇107a）。LAMP1/CD107a屬于LAMP家族。這種糖蛋白為選擇素提供碳水化合物配體。它也可能在腫瘤細(xì)胞轉(zhuǎn)移中發(fā)揮作用。CD107a也被證明是CD8+和NK細(xì)胞等淋巴細(xì)胞脫顆粒的標(biāo)志物。