Human CD300c / LMIR2 Protein, His Tag
分子別名(Synonym)
CD300C,CLM-6,CMRF35-A1,CMRF-35,CMRF35A,IGSF16
表達區(qū)間及表達系統(tǒng)(Source)
Human CD300c, His Tag (CDC-H5224) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Arg 183 (Accession # AAH22279).
Predicted N-terminus: Gly 21
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 18.67 kDa. The protein migrates as 26-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
CMRF35樣分子6(CLM-6)也被稱為CD300抗原樣家族成員C、CMRF35-A1、免疫球蛋白超家族成員16(IgSF16)、CD抗原CD300c,屬于CD300家族。CLM-6含有一個Ig樣V型(免疫球蛋白樣)結(jié)構(gòu)域。TLR7和TLR9配體刺激漿細胞樣樹突狀細胞(pDCs)后,CD300a/c RNA和表面表達下調(diào)。外源性干擾素(IFN)-α下調(diào)CD300a/c表達。CD300a和CD300c在pDCs分泌TNF-α和IFN-α的交叉調(diào)節(jié)中起著重要作用。CD300a和CD300c在NK細胞表面無法區(qū)分。
關(guān)鍵字: CD300c;CD300c蛋白;CD300c重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。