4-氯-3-三氟甲基異氰酸苯酯中文同義詞異氰酸-4-氯-3-（三氟甲基）苯酯;4-氯-3-三氟甲苯異氰酸酯;4-氯-3-三氟甲基異氰酸苯酯;4-氯-3-三氟甲基異氰酸苯酯(索拉非尼中間體);4-氯-3-三氟甲基異氰酸酯;4-氯-3-(三氟甲基)苯;4-氯-3-三氟甲基異氰酸苯酯(索拉菲尼中間體);索拉菲尼中間體英文名稱4-Chloro-3-(trifluoromethyl)phenylisocyanate英文同義詞4-CHLORO-3-(TRIFLUOROMETHYL)PHENYLISOCYANATE;3-TRIFLUOROMETHYL-4-CHLORO-PHENYLISOCYANATE;4-CHLORO-3-(TRIFLUOROMETHYL)PHENYLISOCYANATE98%;1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene;4-Chloro-α,α,α-trifluoro-m-tolylisocyanate;4-Chloro-3-(trifluoromethyl)phenylisocyanate,98%;4-Chloro-3-(trifluoroMethyl)phenylisocyanate,98%5GR;Benzene,1-chloro-4-isocyanato-2-(trifluoromethyl)-CAS號(hào)327-78-6分子式C8H3ClF3NO分子量221.56EINECS號(hào)608-783-6;455-070-9相關(guān)類別醫(yī)藥中間體;瑞格菲尼中間體;索拉菲尼;瑞格菲尼;抗癌藥索拉非尼中間體;索拉非尼側(cè)鏈;合成;抗癌類;原料藥;黃金;其他原料;化工原料;Phenylisocyanate&Phenylisothiocyanate;Isocyanates;NitrogenCompounds;OrganicBuildingBlocks;有機(jī)化學(xué);醫(yī)藥原料;化工中間體;化學(xué)試劑Mol文件327-78-6.mol結(jié)構(gòu)式4-氯-3-三氟甲基異氰酸苯酯性質(zhì)熔點(diǎn)40-42°C(lit.)沸點(diǎn)86-90°C14mmHg(lit.)密度1.4720(estimate)蒸氣壓91Paat20℃閃點(diǎn)211°F儲(chǔ)存條件underinertgas(nitrogenorArgon)at2-8°C溶解度易溶于可溶于氯仿、甲醇形態(tài)低熔點(diǎn)固體、粉末或塊狀顏色白色至黃色敏感性MoistureSensitiveBRN522032InChIInChI=1S/C8H3ClF3NO/c9-7-2-1-5(13-4-14)3-6(7)8(10,11)12/h1-3HInChIKeyAHFPRSSHNSGRCU-UHFFFAOYSA-NSMILESC1(Cl)=CC=C(N=C=O)C=C1C(F)(F)FCAS數(shù)據(jù)庫(kù)327-78-6(CASDataBaseReference)4-氯-3-三氟甲基異氰酸苯酯用途與合成方法用途4-氯-3-三氟甲基異氰酸苯酯是生產(chǎn)抗腫瘤藥物索拉非尼的重要中間體。應(yīng)用4-氯-3-三氟甲基異氰酸苯酯是有機(jī)合成中間體和醫(yī)藥研發(fā)中間體，可用作實(shí)驗(yàn)室有機(jī)合成過(guò)程和醫(yī)藥研發(fā)過(guò)程中。