中文名稱4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯中文同義詞4-(6-氨基-3-吡啶基)-1-BOC-哌嗪;4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯;4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯哌泊塞克雷布中間體;4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯(片段B);瑞博西尼RIBOCICLIB中間體;4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯(帕博西布中間體);4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯1G;瑞博西尼中間體2英文名稱tert-butyl4-(6-aminopyridin-3-yl)piperazine-1-carboxylate英文同義詞1-BOC-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE;OTAVA-BB1207229;4-(6-Aminopyridin-3-yl)piperazine-1-carboxylicacidtert-butylester;1-Piperazinecarboxylicacid,4-(6-aMino-3-pyridinyl)-,1,1-diMethylethylester;tert-butyl4-(6-aMinopyri;4-(6-aMinopyridin-3-yl)piperazine-1-carboxylic;PALBOCICLIB4;2-Methyl-2-propanyl4-(6-amino-3-pyridinyl)-1-piperazinecarboxylateCAS號(hào)571188-59-5分子式C14H22N4O2分子量278.35EINECS號(hào)695-268-4相關(guān)類別帕布昔利布原料一;哌嗪;有機(jī)原料;雜環(huán);帕布昔利布中間體;哌嗪類;帕博西布中間體;帕博西尼中間體;中間體;對(duì)照品-雜質(zhì)對(duì)照品;化工中間體;醫(yī)用原料;醫(yī)藥中間體;PALBOCICLIB中間體;PD0332991;Palbociclib;Anticancer;醫(yī)藥原料;雜質(zhì)對(duì)照品;000-中間體;系列1;瑞博西尼;化學(xué)試劑Mol文件571188-59-5.mol結(jié)構(gòu)式4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯性質(zhì)熔點(diǎn)130-132℃沸點(diǎn)454.1±45.0°C(Predicted)密度1.182蒸氣壓0-0Paat20-25℃儲(chǔ)存條件Keepindarkplace,Inertatmosphere,Roomtemperature溶解度可溶于DMSO（輕微）、甲醇（非常輕微）形態(tài)固體酸度系數(shù)(pKa)7.36±0.26(Predicted)顏色深黃色敏感性AirSensitiveInChIInChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)InChIKeyRMULRXHUNOVPEI-UHFFFAOYSA-NSMILESN1(C(OC(C)(C)C)=O)CCN(C2=CC=C(N)N=C2)CC1LogP1.6-1.8at35℃andpH7-94-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯用途與合成方法外觀4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯呈淡黃至棕色固體狀。應(yīng)用4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯是醫(yī)藥中間體，主要用于合成帕布昔利布原料藥。用途4-(6-氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯是有機(jī)合成中間體和醫(yī)藥中間體，主要作為實(shí)驗(yàn)室研發(fā)和化工醫(yī)藥合成過(guò)程中。