價格 | ¥25500 | ¥19800 | ¥15000 |
包裝 | 100mg | 50mg | 25mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-12 |
中文名稱:化合物 Netarsudil free base | 英文名稱:Netarsudil free base |
CAS:1254032-66-0 | 品牌: TargetMol |
產(chǎn)地: 美國 | 保存條件: Shipping with blue ice. |
產(chǎn)品類別: 抑制劑 | |
貨號: T71119 |
名稱 | Netarsudil free base |
描述 | Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and?/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1?nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16?nM, respectively, and blocked the profibrotic effects of TGF-β2 in HTM cells. Netarsudil produced large reductions in IOP in rabbits and monkeys that were sustained for at least 24?h after once daily dosing, with transient, mild hyperemia observed as the only adverse effect. |
存儲條件 | Shipping with blue ice. |
關(guān)鍵字 | Netarsudil | Netarsudil free base | ABI 274 | ABI274 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 566.265100萬人民幣 |
員工人數(shù) | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 天然產(chǎn)物,生化試劑,分子生物學,分子砌塊,生物技術(shù)服務 | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務 |
產(chǎn)品名稱 | 價格 | 公司名稱 | 報價日期 | |
---|---|---|---|---|
詢價 |
VIP5年
|
深圳菲斯生物科技有限公司
|
2024-12-24 | |
詢價 |
VIP11年
|
成都美域高制藥有限公司
|
2024-12-24 | |
詢價 |
VIP5年
|
陜西締都醫(yī)藥化工有限公司
|
2024-12-18 |