價格 | ¥1270 | ¥9430 | ¥17200 |
包裝 | 1mg | 10mg | 25mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-12 |
中文名稱:CAY10681 | 英文名稱:CAY10681 |
CAS:1542066-69-2 | 品牌: TargetMol |
產地: 美國 | 保存條件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
產品類別: 抑制劑 | |
貨號: T36191 |
名稱 | CAY10681 |
描述 | Inactivation of the tumor suppressor p53 commonly coincides with increased signaling through NF-κB in cancer. CAY10681 is a dual modulator of p53-MDM2 interaction and NF-κB signaling. It potently binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53. CAY10681 also inhibits phosphorylation of IκBα and dose-dependently reduces nuclear accumulation of p65. It blocks the proliferation of cancer cell lines (IC50s range from 33 to 37 μM). CAY10681 exhibits excellent oral bioavailability and inhibits tumor growth in A549 xenografts in nude mice. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 30 mg/mL DMF : 30 mg/mL Ethanol:PBS (pH 7.2) (1:3) : 0.25 mg/mL Ethanol : 30 mg/mL |
關鍵字 | CAY-10681 | CAY10681 | CAY 10681 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 566.265100萬人民幣 |
員工人數 | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 天然產物,生化試劑,分子生物學,分子砌塊,生物技術服務 | 經營模式 | 貿易,工廠,試劑,定制,服務 |
產品名稱 | 價格 | 公司名稱 | 報價日期 | |
---|---|---|---|---|
詢價 |
VIP3年
|
上海嘉定區(qū)澄瀏公路52號
|
2025-01-25 |