價格 | ¥20700 |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2025-02-14 |
中文名稱:APRIL/TNFSF13, Human, 重組蛋白 (Flag & His) | 英文名稱:APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) |
品牌: TargetMol | 產(chǎn)地: 美國 |
保存條件: Lyophilized powder: -20~-80°C for 1 year | Shipping with blue ice. | 純度規(guī)格: 99% |
產(chǎn)品類別: 抑制劑 | |
貨號: TMPJ-00137 |
名稱 | APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) |
描述 | APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL binds to heparan sulfate proteoglycans (HSPGs) independently of its binding to TACI and BCMA. APRIL can form bioactive heterotrimers with BAFF, and these circulate in the serum of patients with rheumatic immune disorders. APRIL enhances the proliferation and survival of plasma cells and also promotes T cell-dependent humoral responses. APRIL levels are elevated in the serum during coronary artery disease, and it is also elevated in many cancers primarily due to expression by tumor-infiltratin neutrophils. |
存儲條件 | Lyophilized powder: -20~-80°C for 1 year | Shipping with blue ice. |
關(guān)鍵字 | CD-256 | TRDL 1 | TALL2 | TALL 2 | CD 256 | TNFSF-13 | TRDL1 | TNFSF 13 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 589.8595萬人民幣 |
員工人數(shù) | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 中間體,天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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